ArticlebioRxiv : the preprint server for biology2024
Deletions Rate-Limit Breast and Ovarian Cancer Initiation.
Kathleen E Houlahan, Mahad Bihie, Julián Grandvallet Contreras, Daniel J Fulop, Gonzalo Lopez, Hsin-Hsiung Huang, Peter Van Loo, Christina Curtis, Paul C Boutros, Kuan-Lin Huang
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Kathleen E HoulahanDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Mahad BihieMcMaster University, Hamilton, Canada.
Julián Grandvallet ContrerasDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Daniel J FulopDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gonzalo LopezDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5092-1284 Hsin-Hsiung HuangDepartment of Statistics, University of Central Florida, Orlando, FL, USA.
Christina CurtisDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Paul C BoutrosDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-0553-7520 Kuan-Lin HuangDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5537-5817 Funding
Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5MIntegrative Approaches for Identifying Causal Gene-Cell Type Pairs of Complex DiseaseR35GM138113 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kuan-lin Huang · 2020 to 2026
$3.0MDevelopment of Protein Biomarkers in Post-DRE Urine for use in Liquid Biopsy of Prostate CancerU01CA214194 · NCI · EASTERN VIRGINIA MEDICAL SCHOOL · PI BOUTROS, PAUL CHRISTOPHER, KISLINGER, THOMAS · 2016 to 2021
$2.5MNCI NIH HHS P30 CA016042NCI NIH HHS U01 CA214194NIGMS NIH HHS R35 GM138113Wellcome Trust CC2008
6 · The paper itselfAbstract
Optimizing prevention and early detection of cancer requires understanding the number, types and timing of driver mutations. To quantify this, we exploited the elevated cancer incidence and mutation rates in germline
Identifiers
PMID39484366
PMCPMC11526986
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