ArticleNeuroSci2023
Toward an Etiology of Spaceflight Neuroplastic Syndrome: Evolutionary Science Leads to New Hypotheses and Program Priorities.
Article in NeuroSci, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evolutionary theory is applied to recent neuroscientific findings on factors associated with risk-and-reward systems, and consequently, aspects of human decision making in spaceflight. Factors include enzymes aiding metabolic pathways of dopamine and serotonin; neurotrophic factors supporting neuronal functioning and plasticity; and genes associated with serotonin and dopamine systems. Not all factors are at risk in spaceflight. Some remain stable. It is hypothesized that neural deconditioning in spaceflight arises from faulty signals sent to the brain and gut in attempting to adapt phenotypically to a novel space environment. There is a mismatch between terrestrial selection pressures during human evolution and conditions of cosmic radiation, microgravity, and higher CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.