Evidence map›Paper›PMID 39483913›Full record

ArticleResearch square2024

Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in

Emma Camacho, Yuemei Dong, Christine Chrissian, Radames J B Cordero, Raúl G Saravia, Yessenia Anglero-Rodriguez, Daniel F Q Smith, Ella Jacobs, Isabelle Hartshorn, Jose Alberto Patiño-Medina and 10 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Emma CamachoJohns Hopkins University, Baltimore, USA.ORCID 0000-0001-8591-8176
Yuemei DongJohns Hopkins University, Baltimore, USA.
Christine ChrissianCity College of New York, New York, USA.
Radames J B CorderoJohns Hopkins University, Baltimore, USA.ORCID 0000-0002-3026-7094
Raúl G SaraviaJohns Hopkins University, Baltimore, USA.ORCID 0000-0002-9847-8277
Yessenia Anglero-RodriguezJohns Hopkins University, Baltimore, USA.
Daniel F Q SmithJohns Hopkins University, Baltimore, USA.ORCID 0000-0002-7674-9988
Ella JacobsJohns Hopkins University, Baltimore, USA.
Isabelle HartshornJohns Hopkins University, Baltimore, USA.
Jose Alberto Patiño-MedinaJohns Hopkins University, Baltimore, USA.
Michael DePasqualeJohns Hopkins University, Baltimore, USA.
Amanda DziedzicJohns Hopkins University, Baltimore, USA.
Anne JedlickaJohns Hopkins University, Baltimore, USA.ORCID 0000-0003-3826-2973
Barbara SmithJohns Hopkins University, Baltimore, USA.
Godfree MlamboJohns Hopkins University, Baltimore, USA.
Abhai TripathiJohns Hopkins University, Baltimore, USA.ORCID 0000-0001-9848-0142
Nichole A BroderickJohns Hopkins University, Baltimore, USA.ORCID 0000-0002-6830-9456
Ruth E StarkCity College of New York, New York, USA.ORCID 0000-0002-3132-4580
George DimopoulosJohns Hopkins University, Baltimore, USA.ORCID 0000-0001-6755-8111
Arturo CasadevallJohns Hopkins University, Baltimore, USA.ORCID 0000-0002-9402-9167

Funding

The biology of Cryptococcus neoformans melanizationR01AI171093 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Arturo Casadevall, JOSHUA D NOSANCHUK · 2023 to 2026
$3.2M
NIAID NIH HHS R01 AI171093
6 · The paper itself

Abstract

L-3,4-dihydroxyphenylalanine (L-DOPA), a naturally occurring tyrosine derivative, is prevalent in environments that include mosquito habitats, potentially serving as part of their diet. Given its role as a precursor for melanin synthesis we investigated the effect of dietary L-DOPA on mosquito physiology and immunity to

Identifiers

PMID39483913
PMCPMC11527263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.