Evidence map›Paper›PMID 39483893›Full record

ArticleResearch square2024

3D Creatine Kinase Imaging (CKI) for In Vivo Whole-Brain Mapping of Creatine Kinase Reaction Rates with

Mark Widmaier, Antonia Kaiser, Pontus Pandurevic, Song-I Lim, Andre Döring, Zhiwei Huang, Daniel Wenz, Ying Xiao, Yun Jiang, Lijing Xin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mark WidmaierCIBM Center for Biomedical Imaging, Switzerland.ORCID https://orcid.org/0009-0000-3353-0305
Antonia KaiserCIBM Center for Biomedical Imaging, Switzerland.ORCID https://orcid.org/0000-0001-7805-6766
Pontus PandurevicCIBM Center for Biomedical Imaging, Switzerland.ORCID https://orcid.org/0009-0008-1835-8197
Song-I LimCIBM Center for Biomedical Imaging, Switzerland.
Andre DöringCIBM Center for Biomedical Imaging, Switzerland.ORCID https://orcid.org/0000-0002-2096-5374
Zhiwei HuangCIBM Center for Biomedical Imaging, Switzerland.
Daniel WenzCIBM Center for Biomedical Imaging, Switzerland.
Ying XiaoCIBM Center for Biomedical Imaging, Switzerland.
Yun JiangDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0001-6737-5016
Lijing XinCIBM Center for Biomedical Imaging, Switzerland.ORCID https://orcid.org/0000-0002-5450-6109

Funding

3D High Resolution Magnetic Resonance Fingerprinting for Prostate CancerR37CA263583 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yun Jiang · 2021 to 2026
$3.8M
Quantitative MRI to automatically delineate intraprostatic tumor for radiation therapyR01CA284172 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI GUO, JIA, JIANG, YUN · 2024 to 2025
$1.4M
NCI NIH HHS R01 CA284172NCI NIH HHS R37 CA263583
6 · The paper itself

Abstract

The creatine kinase (CK) is a key enzyme involved in brain bioenergetics, playing a key role in brain function and the pathogenesis of neurological and psychiatric diseases, but imaging its activity noninvasively in the human brain in vivo remains a significant challenge. This study aims to advance the magnetization transfer (MT)-

Indexed as

31PbioenergeticsCKICreatine Kinase ImagingfCKIfunctional ImagingMRF

Identifiers

PMID39483893
PMCPMC11527232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.