Evidence map›Paper›PMID 39483766›Full record

ArticleNeuroSci2022

Intraclass Correlation in Paired Associative Stimulation and Metaplasticity.

Giuditta Schapira, Justin Chang, Yeun Kim, Jacqueline P Ngo, Choi Deblieck, Valentina Bianco, Dylan J Edwards, Bruce H Dobkin, Allan D Wu, Marco Iacoboni

Abstract read
In one paragraph

Article in NeuroSci, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giuditta SchapiraAhmanson-Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Justin ChangAhmanson-Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Yeun KimAhmanson-Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Jacqueline P NgoAhmanson-Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Choi DeblieckAntwerp Management School, University of Antwerp, 2000 Antwerpen, Belgium.
Valentina BiancoDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00185 Rome, Italy.ORCID https://orcid.org/0000-0003-0044-7075
Dylan J EdwardsMoss Rehabilitation Research Institute, Elkins Park, PA 19027, USA.ORCID https://orcid.org/0000-0001-7346-3100
Bruce H DobkinDepartment of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Allan D WuDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Evanston, IL 60208, USA.
Marco IacoboniAhmanson-Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.ORCID https://orcid.org/0000-0002-0035-5413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paired associative stimulation (PAS) is a widely used noninvasive brain stimulation protocol to assess neural plasticity. Its reproducibility, however, has been rarely tested and with mixed results. With two consecutive studies, we aimed to provide further tests and a more systematic assessment of PAS reproducibility. We measured intraclass correlation coefficients (ICCs)-a widely used tool to assess whether groups of measurements resemble each other-in two PAS studies on healthy volunteers. The first study included five PAS sessions recording 10 MEPS every 10 min for an hour post-PAS. The second study included two PAS sessions recording 50 MEPS at 20 and 50 min post-PAS, based on analyses from the first study. In both studies PAS sessions were spaced one week apart. Within sessions ICC was fair to excellent for both studies, yet between sessions ICC was poor for both studies. We suggest that long term meta-plasticity effects (longer than one week) may interfere with between sessions reproducibility.

Indexed as

long-term potentiationreliabilityspike-timing-dependent plasticitytranscranial magnetic stimulation

Identifiers

PMID39483766
PMCPMC11523748

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.