ArticleCureus2024
The Role of a Biothesiometer in Early Detection and Management of Diabetic Neuropathy.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Diabetic Peripheral Neuropathy: New Diagnostics and Treatment Perspectives.Drugs & aging · 2026Review
- Artificial Intelligence Algorithm to Screen for Diabetic Neuropathy: A Pilot Study.Biomedicines · 2025Article
- Objective perimetry and diabetic retinopathy progression: a 10-year follow-up study.Frontiers in endocrinology · 2025Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionDiabetic foot ulcers (DFUs) have become a common and serious outcome of diabetes mellitus (DM). Diabetic peripheral neuropathy (DPN) is often underdiagnosed, which impairs the capacity to prevent foot ulceration. The clinical manifestations typically include sensory complaints, which leave patients vulnerable to increased risk of injury without their awareness.
aimThe current study aims to assess the viability of VPT (vibration perception threshold) testing using a biothesiometer as an early diagnostic tool for detecting diabetic neuropathy and reducing the burden of diabetic foot disease. MATERIAL AND
methodsThis prospective study was conducted in Dr. D. Y. Patil Medical College, Pimpri, Pune from August 2022 to July 2024 among 50 patients with DFUs. Ethical approval was taken from the Institutional Ethical Committee. An informed consent was obtained from all the study participants. VPT testing using a biothesiometer was done to assess the neurological status of the patient's limbs. A significant difference between the symptomatic and asymptomatic cases was also calculated to evaluate the co-relation of symptoms compared to VPT.
resultsThe largest age group among those surveyed is 41-50 with a mean age of 50.72. Males form a slightly larger proportion than females. A total of 22 (44%) ulcers are present over the plantar aspect of the foot. Out of the entire study, 37 (74%) individuals reported Grade II or III neuropathy, and 29 (58%) individuals reported no symptoms of diabetic neuropathy. The majority portion of individuals in the study had an HbA1c ranging from 6.5% to 8%. After an intervention, 44 (88%) patients did not experience a change in their VPT grading after six months. DISCUSSION: The chi-square test results suggest that the onset period of diabetes in years or the type of treatment history for diabetes does not significantly influence VPT grading among the surveyed individuals. However, individuals with higher HbA1c levels tend to exhibit more severe VPT impairments.
conclusionRegular monitoring of VPT grading is crucial for early diagnosis of neuropathy, tracking disease progression, and assessing intervention effectiveness. Hence, we recommend all diabetic patients regularly undergo biothesiometry as part of their routine diabetic check-ups to help prevent disease progression and complications like amputations and improve their overall quality of life.
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