Evidence map›Paper›PMID 39483536›Full record

ReviewJournal of immunology research2024

Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature.

Angus Nnamdi Oli, Samson Adedeji Adejumo, Adekunle Babajide Rowaiye, Joyce Oloaigbe Ogidigo, Jarrad Hampton-Marcell, Gordon C Ibeanu

Abstract readReview
In one paragraph

Review in Journal of immunology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Immunotherapy for Cancer: Current Advances and Future Directions.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Angus Nnamdi OliDepartment of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka 420211, Nigeria.ORCID https://orcid.org/0000-0001-8519-2555
Samson Adedeji AdejumoDepartment of Biological Sciences, University of Illinois, Chicago, 845 West Taylor, Chicago 60607, Illinois, USA.ORCID https://orcid.org/0000-0001-9971-5193
Adekunle Babajide RowaiyeNational Biotechnology Development Agency, Abuja 900211, Nigeria.ORCID https://orcid.org/0000-0002-8773-5944
Joyce Oloaigbe OgidigoNational Biotechnology Development Agency, Abuja 900211, Nigeria.ORCID https://orcid.org/0000-0003-3323-0657
Jarrad Hampton-MarcellDepartment of Biological Sciences, University of Illinois, Chicago, 845 West Taylor, Chicago 60607, Illinois, USA.ORCID https://orcid.org/0000-0003-1982-4416
Gordon C IbeanuDepartment of Pharmaceutical Science, North Carolina Central University, Durham 27707, North Carolina, USA.ORCID https://orcid.org/0000-0002-7673-2529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. Immunotherapy is preferred to other cancer therapies, offering precise targeting of malignant cells while simultaneously strengthening the immune system's complex responses. Advances in this novel field of science have been closely linked to a deeper knowledge of tumor biology, particularly the intricate interplay between tumor cells, the immune system, and the tumor microenvironment (TME), which are central to cancer progression and immune evasion. This review offers a comprehensive analysis of the molecular mechanisms that govern these interactions, emphasizing their critical role in the development of effective immunotherapeutic products. We critically evaluate the current immunotherapy approaches, including cancer vaccines, adoptive T cell therapies, and cytokine-based treatments, highlighting their efficacy and safety. We also explore the latest advancements in combination therapies, which synergistically integrate multiple immunotherapeutic strategies to overcome resistance and enhance therapeutic outcomes. This review offers key insights into the future of cancer immunotherapy with a focus on advancing more effective and personalized treatment strategies.

Indexed as

Cancer VaccinesImmunotherapyNeoplasmsTumor MicroenvironmentAnimalsCombined Modality TherapyCytokinesHumansImmunotherapy, AdoptiveCancer VaccinesCytokinesbiologicscancerimmune therapyimmunological productsmalignanttumors

Identifiers

PMID39483536
PMCPMC11527548

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.