Evidence map›Paper›PMID 39483428›Full record

ArticleNeuroSci2022

Study Protocol: Strategies and Techniques for the Rehabilitation of Cognitive and Motor Deficits in Patients with Multiple Sclerosis.

Ornella Argento, Chiara Piacentini, Michela Bossa, Carlo Caltagirone, Andrea Santamato, Vincenzo Saraceni, Ugo Nocentini

Abstract read
In one paragraph

Article in NeuroSci, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Motor, cognitive, and combined rehabilitation approaches on MS patients' cognitive impairment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ornella ArgentoBehavioral Neuropsychology Laboratory, I.R.C.C.S. "Santa Lucia" Foundation, 00179 Rome, Italy; c.piacentini@hsantalucia.it (C.P.); m.bossa@hsantalucia.it (M.B.); u.nocentini@hsantalucia.it (U.N.).ORCID https://orcid.org/0000-0001-8153-5573
Chiara PiacentiniBehavioral Neuropsychology Laboratory, I.R.C.C.S. "Santa Lucia" Foundation, 00179 Rome, Italy; c.piacentini@hsantalucia.it (C.P.); m.bossa@hsantalucia.it (M.B.); u.nocentini@hsantalucia.it (U.N.).
Michela BossaBehavioral Neuropsychology Laboratory, I.R.C.C.S. "Santa Lucia" Foundation, 00179 Rome, Italy; c.piacentini@hsantalucia.it (C.P.); m.bossa@hsantalucia.it (M.B.); u.nocentini@hsantalucia.it (U.N.).
Carlo CaltagironeScientific Direction, I.R.C.C.S. "Santa Lucia" Foundation, 00179 Rome, Italy; c.caltagirone@hsantalucia.it.
Andrea SantamatoRehabilitation Centre, Physical Medicine and Rehabilitation Section, OORR Hospital, University of Foggia, 71100 Foggia, Italy; andrea.santamato@unifg.it.ORCID https://orcid.org/0000-0002-1452-8485
Vincenzo SaraceniScientific Direction, "Filippo Turati" Foundation, Rehabilitation Centre, 51100 Pistoia, Italy; vincenzosaraceni@gmail.com.
Ugo NocentiniBehavioral Neuropsychology Laboratory, I.R.C.C.S. "Santa Lucia" Foundation, 00179 Rome, Italy; c.piacentini@hsantalucia.it (C.P.); m.bossa@hsantalucia.it (M.B.); u.nocentini@hsantalucia.it (U.N.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MS clinical features vary between patients. In approximately 60% of cases, cognitive deficits are associated with motor disabilities, with consequences on both walking and maintaining balance and cognitive efficiency. Multimodal programs are very infrequent for MS patients and cognitive rehabilitation is not provided by the Italian health system, which only favors access to motor rehabilitation. Dual-task studies showed how motor and cognitive skills are closely associated. Therefore, physiotherapy exercises may favor an indirect improvement in cognition. The aim of this study is to understand which rehabilitative approach may increase both cognitive and motor efficiency, avoiding the waste of time and resources. In this multi-site single-blind parallel controlled clinical trial, we will compare three rehabilitative approaches: cognitive training, motor training and combined cognitive-motor training. We also aim to evaluate: whether self-perception and objective improvement correspond; the impact of each rehabilitation program on patients' QoL, mood and self-perception; and long-term effects. A total of 60 patients will be randomly assigned to one of the three treatments for two 45-min sessions/week for 12 weeks. All participants will undergo a complete cognitive, motor, clinical assessment together with mood, self-perception, and QoL questionnaires before, immediately after and 6 months after the training period.

Indexed as

memorymultiple sclerosisrehabilitationstudy protocol

Identifiers

PMID39483428
PMCPMC11523688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.