ArticleNeuroSci2022
The Consciousness of Pain: A Thalamocortical Perspective.
Article in NeuroSci, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Perception of first and second pain during offset analgesia.Experimental brain research · 2025Trial
- ADESTI: A portable open source instrument for air quality monitoring in surgical operating rooms.HardwareX · 2026Article
- Electroencephalography, behavioural observations, bleed-out and temperature at the point of application in cattle receiving DTS: Diathermic Syncope® at 160-200 kJ.Veterinary and animal science · 2026Article
- Indicators of loss of consciousness in slaughter without stunning: a neuroanatomical reappraisal.Frontiers in veterinary science · 2026Review
- Review
- Evolutionary Trajectories of Consciousness: From Biological Foundations to Technological Horizons.Brain sciences · 2025Review
- Consciousness Research Through Pain.Healthcare (Basel, Switzerland) · 2025Review
- Article
- Meditation as an Adjunct to the Management of Acute Pain.Current pain and headache reports · 2023Review
- Neuroanatomy of the Will.NeuroSci · 2022Article
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
Deep, dreamless sleep is considered the only "normal" state under which consciousness is lost. The main reason for the voluntary, external induction of an unconscious state, via general anesthesia, is to silence the brain circuitry of nociception. In this article, I describe the perception of pain as a neural and behavioral correlate of consciousness. I briefly mention the brain areas and parameters that are connected to the presence of consciousness, mainly by virtue of their absence under deep anesthesia, and parallel those to brain areas responsible for the perception of pain. Activity in certain parts of the cortex and thalamus, and the interaction between them, will be the main focus of discussion as they represent a common ground that connects our general conscious state and our ability to sense the environment around us, including the painful stimuli. A plethora of correlative and causal evidence has been described thus far to explain the brain's involvement in consciousness and nociception. Despite the great advancement in our current knowledge, the manifestation and true nature of the perception of pain, or any conscious experience, are far from being fully understood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.