Evidence map›Paper›PMID 39483360›Full record

ArticleNeuroSci2022

Bilateral Facial Palsy as the Onset of Neurosarcoidosis: A Case Report and a Revision of Literature.

Chiara Gallo, Letizia Mazzini, Claudia Varrasi, Domizia Vecchio, Eleonora Virgilio, Roberto Cantello

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroSci, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Case Report: A Typical Lyme Disease With Uncommon Neurologic Presentation.Journal of community hospital internal medicine perspectives · 2024
    Article
  4. Featured Papers inNeuroSci · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiara GalloDepartment of Neurology, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy; 20032512@studenti.uniupo.it (C.G.); mazzini.letizia5@gmail.com (L.M.); claudia.varrasi@libero.it (C.V.); domizia.vecchio@gmail.com (D.V.); roberto.cantello@med.uniupo.it (R.C.).
Letizia MazziniDepartment of Neurology, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy; 20032512@studenti.uniupo.it (C.G.); mazzini.letizia5@gmail.com (L.M.); claudia.varrasi@libero.it (C.V.); domizia.vecchio@gmail.com (D.V.); roberto.cantello@med.uniupo.it (R.C.).
Claudia VarrasiDepartment of Neurology, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy; 20032512@studenti.uniupo.it (C.G.); mazzini.letizia5@gmail.com (L.M.); claudia.varrasi@libero.it (C.V.); domizia.vecchio@gmail.com (D.V.); roberto.cantello@med.uniupo.it (R.C.).
Domizia VecchioDepartment of Neurology, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy; 20032512@studenti.uniupo.it (C.G.); mazzini.letizia5@gmail.com (L.M.); claudia.varrasi@libero.it (C.V.); domizia.vecchio@gmail.com (D.V.); roberto.cantello@med.uniupo.it (R.C.).ORCID https://orcid.org/0000-0001-5920-9210
Eleonora VirgilioDepartment of Neurology, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy; 20032512@studenti.uniupo.it (C.G.); mazzini.letizia5@gmail.com (L.M.); claudia.varrasi@libero.it (C.V.); domizia.vecchio@gmail.com (D.V.); roberto.cantello@med.uniupo.it (R.C.).ORCID https://orcid.org/0000-0002-0045-3806
Roberto CantelloDepartment of Neurology, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy; 20032512@studenti.uniupo.it (C.G.); mazzini.letizia5@gmail.com (L.M.); claudia.varrasi@libero.it (C.V.); domizia.vecchio@gmail.com (D.V.); roberto.cantello@med.uniupo.it (R.C.).ORCID https://orcid.org/0000-0001-6999-5729

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unilateral facial nerve palsy (FNP) is one of the most common cranial mononeuropathies. Among rare etiologies, neurosarcoidosis (NS) can cause bilateral involvement (both recurring and simultaneous) only in 15% to 25% of cases. The rarity of this systemic disease and its clinical heterogeneity, due to granulomatous inflammation that may affect many anatomic substrates, frequently make the diagnosis a real challenge for the clinician. Based on laboratory and instrumental tests, a careful diagnostic algorithm must be adopted to avoid misdiagnosis and delay in treatment. We present a 52-year-old woman with an acute onset of unilateral right FNP, rapidly developing contralateral involvement (simultaneous bilateral FNP). Lung findings pointed towards a systemic disease, and then lymph node biopsy confirmed NS. Corticosteroid therapy was started. After three years of follow-up, the patient is still in remission with a low prednisone dose. We discuss the differential diagnosis of bilateral FNP, focusing on clinical presentation, diagnosis, and treatment of NS. We have performed a literature revision, confirming bilateral FNP, outside Heerfordt syndrome, to be rare and sometimes represent the only neurological manifestation of NS onset.

Indexed as

cranial neuropathyfacial diplegialymph node biopsyneurosarcoidosissarcoidosis

Identifiers

PMID39483360
PMCPMC11523723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.