Evidence map›Paper›PMID 39483283›Full record

ArticleNeuroSci2024

Therapeutic Effect of

Dong Hwan Ho, Hyejung Kim, Daleum Nam, Mi Kyoung Seo, Sung Woo Park, Dong-Kyu Kim, Ilhong Son

Abstract read
In one paragraph

Article in NeuroSci, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong Hwan HoInAm Neuroscience Research Center, Sanbon Medical Center, College of Medicine, Wonkwang University, 321, Sanbon-ro, Gunpo-si 15865, Republic of Korea; ceci776@naver.com (H.K.); ekfma304@naver.com (D.N.).ORCID https://orcid.org/0000-0003-4938-4108
Hyejung KimInAm Neuroscience Research Center, Sanbon Medical Center, College of Medicine, Wonkwang University, 321, Sanbon-ro, Gunpo-si 15865, Republic of Korea; ceci776@naver.com (H.K.); ekfma304@naver.com (D.N.).
Daleum NamInAm Neuroscience Research Center, Sanbon Medical Center, College of Medicine, Wonkwang University, 321, Sanbon-ro, Gunpo-si 15865, Republic of Korea; ceci776@naver.com (H.K.); ekfma304@naver.com (D.N.).ORCID https://orcid.org/0000-0002-5165-6849
Mi Kyoung SeoPaik Institute for Clinical Research, Inje University College of Medicine, Busan-si 47392, Republic of Korea; first1011486@hanmail.net (M.K.S.); neuro109@hanmail.net (S.W.P.).ORCID https://orcid.org/0000-0002-3368-4950
Sung Woo ParkPaik Institute for Clinical Research, Inje University College of Medicine, Busan-si 47392, Republic of Korea; first1011486@hanmail.net (M.K.S.); neuro109@hanmail.net (S.W.P.).ORCID https://orcid.org/0000-0001-8601-9084
Dong-Kyu KimDepartment of Ophthalmology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 10, 63-Ro, Yeongdeungpo-Gu, Seoul 07345, Republic of Korea; rockbottom23@hanmail.net.
Ilhong SonInAm Neuroscience Research Center, Sanbon Medical Center, College of Medicine, Wonkwang University, 321, Sanbon-ro, Gunpo-si 15865, Republic of Korea; ceci776@naver.com (H.K.); ekfma304@naver.com (D.N.).ORCID https://orcid.org/0000-0001-9038-1369

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leucine-rich repeat kinase 2 (LRRK2) and α-synuclein are involved in the pathogenesis of Parkinson's disease. The activity of LRRK2 in microglial cells is associated with neuroinflammation, and LRRK2 inhibitors are crucial for alleviating this neuroinflammatory response. α-synuclein contributes to oxidative stress in the dopaminergic neuron and neuroinflammation through Toll-like receptors in microglia. In this study, we investigated the effect of the marine alga

Indexed as

leucine-rich repeat kinase 2neuroinflammationPadina arborescensParkinson’s diseaseα-synuclein

Identifiers

PMID39483283
PMCPMC11469749

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.