Evidence map›Paper›PMID 39483208›Full record

ArticleOpen forum infectious diseases2024

A Single-center Experience of Coccidioides Meningitis in Immunocompetent Patients: Case Series and Literature Review.

Ravi Rajmohan, Jacob Deyell, Mark Harris, Kevin Gramajo-Aponte, Gianna Fote, Jordan Davies, Nita Chen, Catherine Diamond, Xiaoying Lu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ravi RajmohanDepartment of Neurology, University of California, Irvine, California, USA.ORCID https://orcid.org/0000-0001-8066-2757
Jacob DeyellSchool of Medicine, University of California, Irvine, California, USA.
Mark HarrisSchool of Medicine, University of California, Irvine, California, USA.
Kevin Gramajo-AponteSchool of Medicine, University of California, Irvine, California, USA.
Gianna FoteDepartment of Neurosurgery, University of California, Irvine, California, USA.
Jordan DaviesDepartment of Neurosurgery, University of California, Irvine, California, USA.
Nita ChenDepartment of Neurology, University of California, Irvine, California, USA.
Catherine DiamondDepartment of Infectious Diseases, University of California, Irvine, California, USA.
Xiaoying LuDepartment of Neurology, Loma Linda University, Loma Linda, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the California Department of Public Health issued an advisory related to the substantial rise in Coccidioidomycosis in California, which has been attributed in part to climate change and rapid housing development. Most cases are self-limiting, but some may spread to the meninges, resulting in coccidioidal meningitis (CM). Many providers mistakenly presume that CM is limited to patients who are immunocompromised. In this case series and literature review, we present 12 cases of CM in immunocompetent individuals seen at a single tertiary academic center between 1 January 2019 and 31 December 2023. All 12 cases developed complications, with 10 requiring ventriculoperitoneal shunting, 6 having spinal cord involvement (5 with cervical spine involvement), 4 having strokes, and 3 dying from complications related to CM. It is important to recognize CM as it may be life-threatening if not promptly diagnosed.

Indexed as

climate changecoccidioidal meningitiscoccidioidesfungal meningitisimmunocompetence

Identifiers

PMID39483208
PMCPMC11523123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.