ArticleFrontiers in cellular and infection microbiology2024
Isolation and pathogenicity of a highly virulent group III porcine Getah virus in China.
Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- A conserved E1 stem motif functions as a virulence switch in the emerging Getah virus.Virulence · 2026Article
- The 3'Untranslated region is a critical determinant of Getah virus replication, pathogenesis, and vector competence.Virulence · 2026Article
- Potential threats of porcine Getah virus outbreaks and its specific antagonism of host antiviral response through proteasome-dependent degradation of P46 by nsP2.PLoS pathogens · 2026Article
- Isolation and Molecular Characterization of Emerging Getah Virus Genotype III Variant Strains from Swine in Southeastern China (2024-2025).International journal of molecular sciences · 2026Article
- Re-Emergence and Characterization of a Highly Pathogenic Getah Virus on a Pig Farm in Guangdong Province, China.Microorganisms · 2026Article
- Mosquito-borne viral infections: veterinary diagnostic approach with a One Health perspective.Journal of clinical microbiology · 2026Review
- Isolation and Characterization of a Highly Virulent Getah Virus Causing Acute Lethal Infection in Neonatal Piglets.Transboundary and emerging diseases · 2026Article
- Highly Virulent Getah Virus Subgroup GIII-c Emerging in Pigs in China.Transboundary and emerging diseases · 2026Article
- Getah Virus in Review: An Emerging Zoonotic Arbovirus.Transboundary and emerging diseases · 2026Review
- Outbreak and epidemic of Getah virus infection in swine by virulence-enhanced GIII variant in Henan, central China in 2024.Virulence · 2025Article
- Global seroprevalence and distribution of Getah virus in domestic and wild animals: A systematic review and meta-analysis.Veterinary world · 2025Article
- Isolation and Characterization of a Porcine Getah Virus Strain from Sichuan Province.Veterinary sciences · 2025Article
- Getah Virus: A New Contaminant in Veterinary Vaccines.Veterinary sciences · 2025Article
- First report on identification and genetic characterization of Getah virus in wild boar in China.Frontiers in microbiology · 2025Article
- Antiviral activity ofFrontiers in veterinary science · 2025Article
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10 authors.
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Abstract
Introduction: Getah virus (GETV) is a multi-host virus found in pigs, horses, and blue foxes. Clinically, GETV can cause fever, diarrhea, and reproductive disorders in pigs, representing significant threats to pig breeding. At present, few studies have examined the pathogenicity of GETV in pigs of different ages. Methods: In the present study, a new strain, named GETV-QJ, was isolated from clinically ill pigs, and whole genome sequencing analysis was performed. Besides the pathogenicity of piglets and pregnant sows of this strain was further studied. Results: the results illustrated that the strain belonged to group III. The strain had 93.6%-96.3% homology with other subtypes, and its homology with the same subtype strain ranged 96.5%-99%. Further studies on the pathogenicity of the virus indicated that this strain caused severe diarrhea, fever, and intestinal and lung damage in 7-day-old piglets, resulting in their death. The piglet survival rate was 0%. In pregnant sows, this strain did not cause fever, death, or abortion, but it induced viremia, which affected the farrowing performance of sows and led to reduced piglet survival. Discussion: In this study, we isolated a highly virulent group III and comprehensively established a pathogenic model of GETV in piglets and sows, providing a reference and guidance for the prevention and control of this infection.
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