ArticleAnimal bioscience2025
Impacts of replacing soybean meal with processed soybean meal on intestinal health and growth of nursery pigs challenged with F18+ Escherichia coli.
Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Nutritional needs of non-essential amino acids for intestinal health and growth performance of nursery pigs fed diets without soybean meal.Journal of animal science · 2026Article
- Effects of processed soybean meal on growth performance and gut microbiome composition in pigs in regular nursery and enterotoxigenicTranslational animal science · 2026Article
- Impacts of different dietary soybean meal levels on jejunal immunity of nursery pigs at different days post-weaning.Journal of animal science and biotechnology · 2025Article
- Post-weaning diarrhea caused by F18Microbiome research reports · 2025Review
- The Weaning of Pigs: Mechanistic Outcomes to Intestinal Immunity and Integrity.Animal science journal = Nihon chikusan GakkaihoReview
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Authors and funding
3 authors.
Funding
Abstract
objectiveThis study aimed to investigate the impact of different level of soybean meal (SBM) replaced by soy protein concentrate on intestinal health and growth performance of nursery pigs under F18+ Escherichia coli (E. coli).
methodsForty-eight newly weaned pigs (6.6±0.3 kg) were randomly allotted to 4 treatments arranged by 2×2 factors using randomized complete block design with initial body weight and sex as blocks. Two factors were F18+ E. coli challenge (0 or 2.1×1010 colony-forming units [CFU]) and the level of SBM (24% or 12% in phase 1 and 26% or 14% in phase 2). Pigs were fed for 25 d in 2 phases (phase 1 for 11 d and phase 2 for 14 d). At the end of study, all pigs were euthanized to collect jejunal mucosa and tissues.
resultsThe F18+ E. coli challenge decreased (p<0.05) overall average daily gain (ADG) and average daily feed intake (ADFI) and decreased (p<0.05) gain to feed ratio on d 7 to 11. The high SBM tended to have a greater overall ADG (p = 0.054) and ADFI (p = 0.078) compared with low SBM under F18+ E. coli challenge, but not in unchallenged conditions. The F18+ E. coli challenge increased (p<0.05) fecal score on d 7 to 18. The tumor necrosis factor-α and interleukin-1β in jejunal mucosa were decreased (p<0.05) in high SBM treatments. The high SBM tended to increase (p = 0.085) occludin expression in jejunum. high SBM increased crypt depth in jejunum under F18+ E. coli challenge, but not in unchallenged conditions (p<0.05).
conclusionHigh SBM in nursery diets could alleviate the detrimental effects of F18+ E. coli challenge on growth performance of pigs under compared to low SBM inclusion, which might be attributed to decreased intestinal inflammation and improved intestinal integrity.
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