Evidence map›Paper›PMID 39482947›Full record

ArticleThe American journal of psychiatry2024

Disparities in Treatment for Alcohol Use Disorder Among All of Us Participants.

Phuc Le, Jacob James Rich, Eden Y Bernstein, Joseph Glass, Hamlet Gasoyan, Sudie E Back, Thanh C Bui, Gina Ayers, Michael B Rothberg

Abstract read
In one paragraph

Article in The American journal of psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Psychosocial Interventions for Alcohol Use Disorder: A Review of Efficacy, Mechanisms, and Clinical Implications.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Phuc LeCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Jacob James RichCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Eden Y BernsteinCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Joseph GlassCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Hamlet GasoyanCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Sudie E BackCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Thanh C BuiCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Gina AyersCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Michael B RothbergCenter for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).

Funding

Using patient-level decision modeling to improve use of treatments for alcohol use disorderR01AA030970 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI Phuc Le · 2023 to 2026
$2.6M
NIAAA NIH HHS R01 AA030970
6 · The paper itself

Abstract

objectiveThe authors examined racial/ethnic and socioeconomic disparities in receiving treatment for alcohol use disorder (AUD).

methodsA retrospective cohort study was conducted that included adults (≥18 years) with AUD from the All of Us Controlled Tier database v7. Outcomes were lifetime receipt of FDA-approved medications (disulfiram, acamprosate, and naltrexone), psychotherapy (individual, family, and group-based session), and combination treatment (medication and psychotherapy). The study examined treatment receipt by race/ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic, other), insurance (private, Medicare, Medicare and Medicaid, Medicaid, Veteran Affairs [VA], none), income (<$10K, $10-<$50K, $50-$100K, >$100K), and area deprivation index (ADI) quintiles. Multivariable logistic and multinomial logistic regressions were used to assess the association between patient characteristics and treatment receipt.

resultsThe cohort consisted of 18,692 patients (mean age=57.1 years; 60.7% were male; 47.1% were non-Hispanic White). Almost 70% received no treatment, 11.4% received medication, 24.0% received psychotherapy, and 4.9% received combination treatment. In adjusted analysis, non-Hispanic Black (aOR=0.78, 95% CI=0.69-0.89) and Hispanic (aOR=0.75, 95% CI=0.64-0.88) individuals were less likely to receive medication than non-Hispanic White counterparts. There was no association between race/ethnicity and receipt of psychotherapy or combination treatment. Compared with private insurance, dual eligibility was associated with less use of medication, Medicare and Medicaid with less use of medication and combination treatment, and VA and no insurance with more use of psychotherapy and combination treatment. Higher income and lower ADI were positively associated with all treatment types.

conclusionsThere are disparities in AUD treatment by race/ethnicity, socioeconomic status, and insurance. Systematic approaches are required to improve equitable access to effective treatment.

Indexed as

AcamprosateAlcohol DeterrentsHealthcare DisparitiesPsychotherapyAdultAgedAlcoholismBlack or African AmericanDisulfiramFemaleHispanic or LatinoHumansMaleMedicaidMedicareMiddle AgedAcamprosateAlcohol DeterrentsDisulfiramNaltrexonealcohol use disorderAll of Us programdisparitiespharmacotherapypsychotherapy

Identifiers

PMID39482947
PMCPMC11632673

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.