Evidence map›Paper›PMID 39482921›Full record

ReviewAnti-cancer agents in medicinal chemistry2025

A Review of Anticancer Potential of Conferone, Diversin and Ferutinin; Which One is Stronger for Cancer Therapy?

Fariborz Keshmirshekan, Seyed-Mahdi Mohamadi-Zarch, Seyyed Majid Bagheri

Abstract readReview
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In one paragraph

Review in Anti-cancer agents in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fariborz KeshmirshekanYazd Neuroendocrine Research Center, Faculty of Medeicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Seyed-Mahdi Mohamadi-ZarchYazd Neuroendocrine Research Center, Faculty of Medeicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Seyyed Majid BagheriYazd Neuroendocrine Research Center, Faculty of Medeicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.

Funding

Shahid Sadoughi University of Medical Science and Health Services 17753
6 · The paper itself

Abstract

backgroundOne of the growing diseases in today's human societies is cancer, which has become a major challenge, especially in industrialized and developing countries. Cancer treatments are diverse, but they usually use surgery, chemotherapy, and radiotherapy to improve patients. Existing drugs are usually expensive and, in some cases, are not effective due to drug resistance and side effects. Finding compounds of natural origin can be somewhat effective and useful in helping doctors to treat this disease.

objectiveThis article was compiled with the aim of collecting evidence and articles related to the anti-cancer effects of three compounds obtained from these plants, namely Conferone, Diversin, and Ferutinin.

methodsThis review article was prepared by searching the terms Conferone, Diversin, Ferutinin and cancer and related information was collected through searching electronic databases such as ISI Web of Knowledge, PubMed and Google Scholar until the March of 2024.

conclusionThe results of this review showed that relatively comprehensive studies have been conducted in this field and these studies have shown that these compounds can be used in the design of future anticancer drugs. Among the examined compounds, conferone showed that it has the best effect on cancer cells.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicBridged Bicyclo CompoundsCycloheptanesGlucosidesNeoplasmsSesquiterpenesAnimalsBenzoatesCell ProliferationDrug Screening Assays, AntitumorFerulaHumansMolecular StructureStructure-Activity Relationship4-oxy-6-(4-oxybezoyloxy)dauc-8,9-enAntineoplastic AgentsAntineoplastic Agents, PhytogenicBenzoatesBridged Bicyclo CompoundsCycloheptanesGlucosidesSesquiterpenesanticancer mechanisms.cancerconferonediversinFerulaferutinin

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.