Evidence map›Paper›PMID 39482906›Full record

ReviewReviews on recent clinical trials2025

Non-alcoholic Wernicke Encephalopathy in a Young Patient with Adenocarcinoma of the Colon: A Case Report and Review of the Literature.

Afroditi Ziogou, Andreas Lymperis, Nikolaos Skouteris, Georgios Papageorgiou, Nikolaos Charalampakis

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Reviews on recent clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Afroditi ZiogouDepartment of Medical Oncology, Metaxa Memorial Cancer Hospital, 18537, Piraeus, Greece.ORCID 0009-0008-5853-5522
Andreas LymperisDepartment of Medical Oncology, Metaxa Memorial Cancer Hospital, 18537, Piraeus, Greece.
Nikolaos SkouterisDepartment of Medical Oncology, Metaxa Memorial Cancer Hospital, 18537, Piraeus, Greece.
Georgios PapageorgiouDepartment of Medical Oncology & Hematopoietic Cell Transplant Unit, Metaxa Memorial Cancer Hospital, 18537, Piraeus, Greece.
Nikolaos CharalampakisDepartment of Medical Oncology, Metaxa Memorial Cancer Hospital, 18537, Piraeus, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWernicke Encephalopathy (W.E.) is an acute neurological disorder induced by thiamine deficiency. Alcohol abuse is considered to be the leading cause of the disease; however, numerous other conditions, such as malnutrition or cancer, have been identified as potential risk factors. CASE PRESENTATION: Clinical manifestations include a typical triad of mental status alteration, nystagmus, and ataxia and are attributed to damage in brain regions of high thiamine demand. The diagnosis is mainly clinical and further supported by the immediate response of neurological signs to parenteral thiamine administration. Among paraclinical examinations, brain MRI is considered substantial for diagnosis and is supported by the determination of thiamine blood levels.

conclusionNon-alcoholic W.E. is trickier to diagnose due to its atypical clinical course and risk factors. We herein describe a case of non-alcoholic W.E. in a woman with colon cancer who gradually developed the classic symptoms of thiamine deficiency.

Indexed as

AdenocarcinomaColonic NeoplasmsThiamine DeficiencyWernicke EncephalopathyFemaleHumansMagnetic Resonance ImagingThiamineThiamineadenocarcinomacancercolonneurological disorder.thiamineWernicke encephalopathy

Identifiers

PMID39482906

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.