Evidence map›Paper›PMID 39482693›Full record

ArticleBMC public health2024

Exploring the association between lifestyle and cardiovascular health metrics and HPV infection risk: insights from the National Health and Nutrition Examination Survey 2005-2016 data.

Xiangliang Liu, Yu Chang, Yuguang Li, Yue Qi, Wenshuo Zhou, Wei Ji, Wei Li, Jiuwei Cui

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiangliang Liu *Cancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China.
Yu Chang *Department of Gastroenterology, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China.
Yuguang Li *Cancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China.
Yue QiReproductive Medicine Prenatal Genetics Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China.
Wenshuo ZhouCancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China.
Wei JiCancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China. jiwei324@qq.com.
Wei LiCancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China. liwei66@jlu.edu.cn.
Jiuwei CuiCancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China. cuijw@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman Papillomavirus (HPV) infection has garnered significant attention due to its high prevalence and association with various cancers and other health conditions. Composite lifestyle factors may influence the risk of HPV infection, yet their cumulative impact remains insufficiently explored. This study aims to explore the association between the Life's Essential 8 (LE8) Score and HPV infection status, highlighting the potential role of lifestyle and health behaviors in HPV infection prevention.

methodsUtilizing data from the National Health and Nutrition Examination Survey (NHANES) spanning 2005-2016, we analyzed the health and nutritional statuses of 6,773 participants after excluding those with missing HPV infection status, inability to calculate the LE8 Score, and missing covariate data. The LE8 Score was computed based on eight cardiovascular health metrics, encompassing both health factors (BMI, non-HDL cholesterol, blood pressure, and blood glucose) and health behaviors (physical activity, diet, sleep duration, and nicotine exposure). HPV infection status was determined through vaginal swab specimens analyzed using various Roche assays. Multivariate logistic regression, the restricted cubic splines (RCS) analysis and weighted quantile sum (WQS) regression were employed to assess the association between LE8 Score and HPV infection risk.

resultsOur findings indicate a significant inverse association between the LE8 Score and HPV infection risk. Participants with medium and high LE8 Scores exhibited a 21% and 31% lower risk of HPV infection, respectively, compared to those with low LE8 Scores in multivariate logistic regression models. The analysis also revealed that lifestyle factors, particularly nicotine exposure and blood pressure, significantly contributed to the observed association.

conclusionThe study underscores the importance of healthy lifestyle behaviors in reducing the risk of HPV infection. Public health strategies promoting such behaviors could complement existing HPV prevention measures, potentially lowering the burden of HPV-related diseases. Future research should further investigate the mechanisms underlying this association and the effectiveness of lifestyle interventions in diverse populations.

Indexed as

Life StyleNutrition SurveysPapillomavirus InfectionsAdultCardiovascular DiseasesFemaleHealth BehaviorHumansMaleMiddle AgedRisk FactorsUnited StatesYoung AdultCardiovascular health (CVH)HPV InfectionLife’s essential 8Lifestyle BehaviorsNHANESPublic health strategies

Identifiers

PMID39482693
PMCPMC11529321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.