Evidence map›Paper›PMID 39482640›Full record

ArticleBMC psychiatry2024

The relationship between uncertainty and fear of disease progression among newly diagnosed cancer patients: the mediating role of intolerance of uncertainty.

Zhiying Shen, Li Zhang, Shuangjiao Shi, Chunhong Ruan, Li Dan, Chengyuan Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  8. Intolerance of uncertainty and attitudes toward cancer as predictors of spiritual well-being in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiying ShenDepartment of Hematology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Li ZhangNursing Department, the Fourth Hospital of Changsha, Changsha, Hunan, China.
Shuangjiao ShiDepartment of Hematology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chunhong RuanDepartment of Hematology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Li DanDepartement of Gynaecology, the Fourth Hospital of Changsha, Changsha, Hunan, China.
Chengyuan LiDepartment of Hematology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China. lichengyuan_xy3@163.com.

Funding

the China Scholarship Council program [2023]54the General project of Hunan Health Commission B202314018897the Natural Science Foundation of Hunan Province 2023JJ40884
6 · The paper itself

Abstract

backgroundOne of the most prevalent unmet needs among cancer patients is the fear of disease progression (FoP). This cross-sectional study aimed to identify the relationships among uncertainty in illness (UI), intolerance of uncertainty (IU), and FoP among newly diagnosed cancer patients and to verify the mediating role of IU in the relationship between UI and FoP.

methodsA total of 202 newly diagnosed cancer patients (male: 105, 51.98%; mean age: 47.45 ± 14.8 years; lung cancer: 49, 24.26%) were recruited by convenience sampling. The patients completed a homemade questionnaire that assessed demographic characteristics, the Fear of Progression Questionnaire-Short Form, the Mishel Uncertainty in Illness Scale, and the Intolerance of Uncertainty Scale.

resultsThe prevalence of FoP among newly diagnosed cancer patients was 87.62%, and the prevalences of high, medium, and low levels of UI were 15.84%, 73.27%, and 10.89%, respectively. The mean score on the Intolerance of Uncertainty Scale was 41.19 ± 10.11. FoP among newly diagnosed cancer patients was positively correlated with UI (r = 0.656, P < 0.001) and IU (r = 0.711, P < 0.001). Moreover, IU was positively correlated with UI (r = 0.634, P < 0.001). IU partially mediated the effect of UI on FoP, accounting for 47.60% of the total effect.

conclusionsNewly diagnosed cancer patients have a high prevalence of FoP. UI can directly or indirectly affect FoP through the mediating role of IU. Healthcare professionals can help newly diagnosed cancer patients mitigate their FoP by reducing IU in light of UI.

Indexed as

Disease ProgressionFearNeoplasmsAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceSurveys and QuestionnairesUncertaintyFear of Disease ProgressionIntolerance of uncertaintyNewly diagnosed CancerUncertainty in illness

Identifiers

PMID39482640
PMCPMC11526518

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.