Evidence map›Paper›PMID 39482607›Full record

ArticleBMC pediatrics2024

Cerebral palsy: potential risk factors and functional status among children under three years, a case-control study in northwest Iran.

Morteza Haramshahi, Vahideh Toopchizadeh, Samira Pourzeinali, Neda Nikkhesal, Tahereh Sefidi Heris, Azizeh Farshbaf-Khalili, Shirin Osouli-Tabrizi

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Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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4citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Morteza HaramshahiFaculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Vahideh ToopchizadehPhysical Medicine and Rehabilitation Research Centre, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Samira PourzeinaliAmiralmomenin Hospital of Charoimagh, Vice Chancellor for Treatment, Tabriz University of Medical Sciences, Tabriz, Iran.
Neda NikkhesalMidwifery Department, Islamic Azad University, Bonab Branch, Bonab, Iran.
Tahereh Sefidi HerisPediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Azizeh Farshbaf-KhaliliPhysical Medicine and Rehabilitation Research Centre, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran. farshbafa@tbzmed.ac.ir.
Shirin Osouli-TabriziStudent Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical Science, Tabriz, Iran. shirin.osouli@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral palsy (CP) is one of the most common motor-postural disorders in childhood. It occurs due to impairment in the developing brain-before, during, or after birth-and has a significant burden on the public health system. This study aimed to investigate the potential risk factors and detect the associated CP-related disorders.

methodsThis case-control study was conducted on 46 children with CP and 175 matched healthy children less than three years old who referred to the Children's Hospital, Tabriz, Iran in 2022. Then, a checklist related to the mother's medical history during current and previous pregnancies, a questionnaire related to perinatal factors of the newborn, types of CP, concurrent disorders, the Gross Motor Function Classification System (GMFCS), and Age and Stage Questionaire (ASQ) were completed. Data was analyzed using Statistical Package for the Social Sciences) SPSS(-21 software by descriptive and analytical statistics consisted of Chi-square, Independent t-test, and Binary logistic regression.

resultsFinally, 35 children with CP and 122 healthy children completed the study and were analyzed. The mean (standard deviation: SD) age of children in the CP group was 15.3 (6.2) and in the healthy group was 14.4 (6.6) months (p = 0.635). Spastic CP (82.9%) was the common type, and the most common prevailing form of the involved limb was quadriplegia (54.3%). The severity of the functional disorder in 39.3% of CP cases was at levels 4 and 5 (severe form). The most prevalent comorbidities were inability to walk (31.4%), speech delay (22.9%), epilepsy (11.4), and strabismus (8.6%). Children with CP had abnormal development in gross motor (82.9%), problem-solving (68.6%), personal-social (65.7%), fine motor (60%), and communication (54.3%). Moreover, duration of pregnancy (p = 0.023), birth weight lower than 2500 g (p = 0.002), problems in the current pregnancy [adjusted odds ratio (aOR) [95% CI]: 3.06 (1.87 to 8.54); p = 0.013] and problems in previous pregnancy ([aOR (95% CI): 4.8 (1.6 to 14.2); p = 0.005) were potential risk factors.

conclusionDue to accompanying movement, vision, and speech problems, especially high developmental disorders in children with CP, necessary measures to prevent the identified risk factors are very important.

Indexed as

Cerebral PalsyCase-Control StudiesChild, PreschoolFemaleHumansInfantInfant, NewbornIranMaleRisk FactorsCerebral palsyFunctional statusIranNeurodevelopmentRisk factorsYoung children

Identifiers

PMID39482607
PMCPMC11526636

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