Evidence map›Paper›PMID 39482539›Full record

ArticleExperimental & molecular medicine2024

The transcription factor BBX regulates phosphate homeostasis through the modulation of FGF23.

Su Jeong Lee, Ju Ang Kim, Hye Jung Ihn, Je-Yong Choi, Tae-Yub Kwon, Hong-In Shin, Eui-Sic Cho, Yong Chul Bae, Rulang Jiang, Jung-Eun Kim and 1 more

Abstract read
In one paragraph

Article in Experimental & molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Su Jeong LeeDepartment of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration (IHBR), Kyungpook National University, Daegu, Republic of Korea.
Ju Ang KimDepartment of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration (IHBR), Kyungpook National University, Daegu, Republic of Korea.
Hye Jung IhnCell and Matrix Research Institute, Kyungpook National University, Daegu, Republic of Korea.
Je-Yong ChoiDepartment of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0002-5057-8842
Tae-Yub KwonDepartment of Dental Biomaterials, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Hong-In ShinDepartment of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration (IHBR), Kyungpook National University, Daegu, Republic of Korea.
Eui-Sic ChoCluster for Craniofacial Development and Regeneration Research, Institute of Oral Biosciences, School of Dentistry, Jeonbuk National University, Jeonju, Republic of Korea.
Yong Chul BaeDepartment of Oral Anatomy and Neurobiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Rulang JiangDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Ohio, TX, USA.
Jung-Eun KimCell and Matrix Research Institute, Kyungpook National University, Daegu, Republic of Korea.
Eui Kyun ParkDepartment of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration (IHBR), Kyungpook National University, Daegu, Republic of Korea. epark@knu.ac.kr.

Funding

National Research Foundation of Korea (NRF) 2017R1A2B4003612National Research Foundation of Korea (NRF) 2017R1A5A2015391National Research Foundation of Korea (NRF) RS-2023-00241950
6 · The paper itself

Abstract

Fibroblast growth factor 23 (FGF23) plays an important role in phosphate homeostasis, and increased FGF23 levels result in hypophosphatemia; however, the molecular mechanism underlying increased FGF23 expression has not been fully elucidated. In this study, we found that mice lacking the bobby sox homolog (Bbx

Indexed as

Fibroblast Growth Factor-23Fibroblast Growth FactorsHomeostasisMice, KnockoutPhosphatesAnimalsGene Expression RegulationMiceOsteocytesPromoter Regions, GeneticSodium-Phosphate Cotransporter Proteins, Type IIaTranscription FactorsUbiquitinationFgf23 protein, mouseFibroblast Growth Factor-23Fibroblast Growth FactorsPhosphatesSlc34a1 protein, mouseSodium-Phosphate Cotransporter Proteins, Type IIaTranscription Factors

Identifiers

PMID39482539
PMCPMC11612488

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.