Evidence map›Paper›PMID 39482528›Full record

ArticleParasitology research2024

Fasciola hepatica and Fasciola hybrid form co-existence in yak from Tibet of China: application of rDNA internal transcribed spacer.

Wenqiang Tang, Yule Zhou, Leyi Li, Bin Shi, Xialing Zhao, Kai Li, Wenting Chui, Jun Kui, Fuqiang Huang

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Article in Parasitology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Wenqiang TangState Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, China.
Yule ZhouSchool of Animal Science and Technology, Foshan University, Foshan, China.
Leyi LiSchool of Animal Science and Technology, Foshan University, Foshan, China.
Bin ShiState Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, China.
Xialing ZhaoState Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, China.
Kai LiSchool of Animal Science and Technology, Foshan University, Foshan, China.
Wenting ChuiAnimal Disease Prevention and Control Center of Qinghai Province, Xining, China.
Jun KuiHuangzhong District Animal Husbandry and Veterinary Station, Xining, China.
Fuqiang HuangState Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, China. qxhuangfuqiang@fosu.edu.cn.

Funding

Base and Talent Program of Science and Technology Plan in Tibet Autonomous Region XZ202401JD0012The State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement XZNKY-CZ-2022-016-08
6 · The paper itself

Abstract

Fasciolosis is a parasitic disease affecting humans and livestock, caused by digenean trematodes of the genus Fasciola, primarily F. hepatica and F. gigantica. This study investigates the coexistence of these species and their hybrids in yaks from Tibet, China. We analyzed the nuclear rDNA internal transcribed spacer (ITS) regions, including ITS1 and ITS2, through Sanger sequencing and Next-Generation Sequencing (NGS) to assess single-nucleotide polymorphisms (SNPs). Our results reveal that one specimen (NM008B) is identical to pure F. hepatica, while another (NM008A) contains genetic information from both F. hepatica and F. gigantica, indicating potential hybridization or introgression. The morphological analysis reveals that the collected adult F. hepatica specimens exhibit distinct characteristics, while the hybrid specimens display "intermediate" features of F. hepatica and F. gigantica. This study is the first to document the coexistence of F. hepatica and hybrid Fasciola forms in a single yak. The findings underscore the complexities of hybridization dynamics and the necessity for advanced molecular techniques in accurately identifying Fasciola species. Future research should focus on mitochondrial DNA and other nuclear gene analysis to further elucidate the nature of these hybrids and their ecological implications.

Indexed as

Cattle DiseasesDNA, Ribosomal SpacerFasciolaFascioliasisAnimalsCattleDNA, HelminthFasciola hepaticaHigh-Throughput Nucleotide SequencingHybridization, GeneticPolymorphism, Single NucleotideSequence Analysis, DNATibetDNA, HelminthDNA, Ribosomal SpacerFasciolaNuclear rDNA internal transcribed spacerSingle-nucleotide polymorphismsTibet

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.