ReviewInternational journal of oral science2024
Personalized bioceramic grafts for craniomaxillofacial bone regeneration.
Review in International journal of oral science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Dimensional Accuracy and Clinical Fitness of Customized 3D-Printed Hydroxyapatite Bone Block Grafts in Alveolar Ridge Augmentation.European journal of dentistry · 2026Article
- 3D-Printed Poly(Lactic-co-Glycolic Acid) Binder-Based Self-Hardening Calcium Phosphate Bone Scaffolds.Bioengineering (Basel, Switzerland) · 2026Article
- Artificial Intelligence and Digital Workflow in Craniofacial Bone Tissue Engineering: From Cone-Beam Computed Tomography (CBCT) to Personalized Bioceramic Implants.Dentistry journal · 2026Review
- Applications of DNA Hydrogels in Osteoporotic Bone Defects.Journal of functional biomaterials · 2026Review
- From Static Scaffolds to Responsive Implants: 3D-Printed Field-Active Bioceramics for Adaptive Bone Regeneration.Advanced healthcare materials · 2026Review
- Sustained Release of Carvacrol Aldehyde from Hydroxyapatite for Osteosarcoma Inhibition.Molecular pharmaceutics · 2026Article
- Three-Dimensional Printing and Personalized Bioceramic Scaffolds for Dental and Maxillofacial Applications: A Narrative Review.Dentistry journal · 2026Review
- Calcium-enriched mesoporous silica/PLGA scaffolds enhance bone repair in a rabbit femoral condylar defect model.Scientific reports · 2026Article
- Multifunctional FePharmaceutics · 2026Article
- Mastoid Obliteration After Canal Wall Down Mastoidectomy Using Tissue Engineering Approaches with Polymers, Mesenchymal Stem Cells, and Bioactive Molecules: A Systematic Review.Bioengineering (Basel, Switzerland) · 2026Review
- Bone Tissue Engineering: Recent Advances and Translation to Clinical Application.Journal of functional biomaterials · 2026Article
- Biodegradable and osteoconductive sodium alginate-gelatin/amorphous magnesium phosphate 3D-printed scaffolds for craniofacial bone regeneration.Journal of the mechanical behavior of biomedical materials · 2026Article
- A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Recent advances in biomaterials for bone regeneration: Bridging innovation and clinical translation.Materials today. Bio · 2026Review
- Investigation on Mechanical Properties of Functional Graded Hybrid TPMS Structures Inspired Bone Scaffolds.Polymers · 2026Article
- Next-generation craniomaxillofacial implants for reconstructive surgery: balancing biomechanics, biocompatibility, and bioactivity.International journal of oral science · 2026Review
- Advances in 3D Printed Scaffolds for Periodontal Regeneration.Current oral health reports · 2026Review
- Advances in Composite Bioactive Scaffolds for Alveolar Bone Repair: Implications for Oral Surgery.Brazilian dental journal · 2026Review
- RefinedFrontiers in bioengineering and biotechnology · 2026Article
- Three-Dimensional Printing of Calcium Phosphate-Mesoporous Bioactive Glass Scaffolds for Bone Tissue Engineering.Journal of functional biomaterials · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
The reconstruction of craniomaxillofacial bone defects remains clinically challenging. To date, autogenous grafts are considered the gold standard but present critical drawbacks. These shortcomings have driven recent research on craniomaxillofacial bone reconstruction to focus on synthetic grafts with distinct materials and fabrication techniques. Among the various fabrication methods, additive manufacturing (AM) has shown significant clinical potential. AM technologies build three-dimensional (3D) objects with personalized geometry customizable from a computer-aided design. These layer-by-layer 3D biomaterial structures can support bone formation by guiding cell migration/proliferation, osteogenesis, and angiogenesis. Additionally, these structures can be engineered to degrade concomitantly with the new bone tissue formation, making them ideal as synthetic grafts. This review delves into the key advances of bioceramic grafts/scaffolds obtained by 3D printing for personalized craniomaxillofacial bone reconstruction. In this regard, clinically relevant topics such as ceramic-based biomaterials, graft/scaffold characteristics (macro/micro-features), material extrusion-based 3D printing, and the step-by-step workflow to engineer personalized bioceramic grafts are discussed. Importantly, in vitro models are highlighted in conjunction with a thorough examination of the signaling pathways reported when investigating these bioceramics and their effect on cellular response/behavior. Lastly, we summarize the clinical potential and translation opportunities of personalized bioceramics for craniomaxillofacial bone regeneration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.