Evidence map›Paper›PMID 39482254›Full record

ArticleJournal of veterinary internal medicine

Association among raised intraventricular pressure, clinical signs, and magnetic resonance imaging findings in dogs with congenital internal hydrocephalus.

Daniela Farke, Agnieszka Olszewska, Kathrin Büttner, Martin J Schmidt

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniela FarkeDepartment of Veterinary Clinical Sciences, Small Animal Clinic, Justus-Liebig-University, Frankfurter Strasse 108, Giessen 35392, Germany.ORCID https://orcid.org/0000-0002-6007-332X
Agnieszka OlszewskaDepartment of Veterinary Clinical Sciences, Small Animal Clinic, Justus-Liebig-University, Frankfurter Strasse 108, Giessen 35392, Germany.
Kathrin BüttnerUnit for Biomathematics and Data Processing, Faculty of Veterinary Medicine, Justus Liebig-University-Giessen, Giessen, Germany.
Martin J SchmidtDepartment of Veterinary Clinical Sciences, Small Animal Clinic, Justus-Liebig-University, Frankfurter Strasse 108, Giessen 35392, Germany.ORCID https://orcid.org/0000-0002-3481-4737

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDogs with internal hydrocephalus do not necessarily have high intraventricular pressure (IVP). HYPOTHESIS/

objectivesNot all reported MRI findings indicate high IVP and some clinical signs might be associated with elevated IVP and syringomyelia. ANIMALS: Fifty-three dogs. MATERIALS AND

methodsCross-sectional study. Clinical signs and MRI findings were evaluated for an association of IVP >12 mm Hg and syringomyelia.

resultsHigh IVP was associated with obtundation OR 4.64 (95% CI 1.27-16.93) (P = .02), head tilt OR 6.42 (95% CI 1.08-37.97) (P = .04) and nystagmus OR 8.24 (95% CI 1.44-47.07) (P = .02). Pain was associated with syringomyelia OR 3.4 (95% CI 0.98-11.78) (P = .05). The number of affected ventricles was associated with high IVP OR 2.85 (95% CI 0.97-8.33) (P = .05) and syringomyelia OR 12.74 (95% CI 2.93-55.4) (P = .0007). Periventricular edema OR 24.46 (95% CI 4.54-131.77), OR 7.61 (95% CI 1.91-30.32) (P < .0002, P = .004) and signal void sign OR 17.34 (95% CI 4.01-74.95), OR 4.18 (95% CI 1.16-15.02) (P < .0001, P = .03) were associated with high IVP and syringomyelia. The probability for syringomyelia is lower with disruption of the internal capsule OR 0.19 (95% CI 0.05-0.72) (P = .01) and higher VBR OR 0.25 (95% CI 0.1-0.63) (P = .004). CONCLUSIONS AND CLINICAL IMPORTANCE: Previously reported MRI findings are not predictive of high IVP. Clinical signs and MRI findings should be used to make a diagnosis of internal hydrocephalus in dogs with or without high IVP.

Indexed as

Dog DiseasesHydrocephalusMagnetic Resonance ImagingSyringomyeliaAnimalsCross-Sectional StudiesDogsFemaleMaleVentricular Pressurehydrocephalusintraventricular pressureMRI

Identifiers

PMID39482254
PMCPMC11586545

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.