Evidence map›Paper›PMID 39481890›Full record

ReviewAJNR. American journal of neuroradiology2025

Comprehensive Review of the Utility of Dynamic Contrast-Enhanced MRI for the Diagnosis and Treatment Assessment of Spinal Benign and Malignant Osseous Disease.

Atin Saha, Haley Gibbs, Kyung K Peck, Onur Yildirim, Parsa Nilchian, Sasan Karimi, Eric Lis, Vilma Kosović, Andrei I Holodny

Abstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review Article: Diagnostic Paradigm Shift in Spine Surgery.Diagnostics (Basel, Switzerland) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Atin SahaFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York sahaa@mskcc.org.ORCID 0000-0001-8446-6315
Haley GibbsFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0009-0008-8217-8035
Kyung K PeckDepartment of Medical Physics (K.K.P.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-9841-3078
Onur YildirimFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-1586-1933
Parsa NilchianFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-1460-5946
Sasan KarimiFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-5913-3551
Eric LisFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-4138-3867
Vilma KosovićDepartment of Radiology (V.K.), General Hospital Dubrovnik, Dubrovnik, Croatia.
Andrei I HolodnyFrom the Departments of Radiology (A.S., H.G., O.Y., P.N., S.K., E.L., A.I.H.), Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-1159-2705

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Weill Cornell/Rockefeller/Sloan Kettering MST ProgramT32GM152349 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KATHARINE C HSU · 2024 to 2026
$6.6M
NCI NIH HHS P30 CA008748NIGMS NIH HHS T32 GM152349
6 · The paper itself

Abstract

Conventional MRI is currently the preferred imaging technique for detection and evaluation of malignant spinal lesions. However, this technique is limited in its ability to assess tumor viability. Unlike conventional MRI, dynamic contrast-enhanced (DCE) MRI provides insight into the physiologic and hemodynamic characteristics of malignant spinal tumors and has been utilized in different types of spinal diseases. DCE has been shown to be especially useful in the cancer setting; specifically, DCE can discriminate between malignant and benign vertebral compression fractures as well as between atypical hemangiomas and metastases. DCE has also been shown to differentiate between different types of metastases. Furthermore, DCE can be useful in the assessment of radiation therapy for spinal metastases, including the prediction of tumor recurrence. This review considers data analysis methods utilized in prior studies of DCE-MRI data acquisition and clinical implications.

Indexed as

Contrast MediaImage EnhancementMagnetic Resonance ImagingSpinal DiseasesSpinal NeoplasmsHumansContrast Media

Identifiers

PMID39481890
PMCPMC11979806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.