Evidence map›Paper›PMID 39480631›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024

High release of Candida albicans eDNA as protection for the scaffolding of polymicrobial biofilm formed with Staphylococcus aureus and Streptococcus mutans against the enzymatic activity of DNase I.

Santiago M Lattar, Rene Peter Schneider, Vidal Jorge Eugenio, Gabriel Padilla

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Santiago M LattarCell Biology of Microorganism Laboratory, Department of Microbiology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, BH, Brazil. santiagolattar@gmail.com.ORCID http://orcid.org/0000-0001-5703-8024
Rene Peter SchneiderPolytechnic School, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-8578-1966
Vidal Jorge EugenioDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS, USA.ORCID http://orcid.org/0000-0003-0573-5658
Gabriel PadillaBioproducts Laboratory, Department of Microbiology, Institute of Biomedical Science, University of São Paulo, São Paulo, SP, Brazil. gpadilla@icb.usp.br.ORCID http://orcid.org/0000-0001-8086-3065

Funding

FAPESP 2017/07339-4FUNDEP 30201*52
6 · The paper itself

Abstract

This study aimed to determine the protective role of the high release of C. albicans extracellular DNA (eDNA) in a polymicrobial biofilm formed by S. aureus and S. mutans in the course of DNase I treatment. A tube-flow biofilm bioreactor was developed to mimic biofilm formation in the oral cavity. eDNA release was quantified by real-time PCR (qPCR) and confocal microscopy analysis were used to determine the concentration and distribution of eDNA and intracellular DNA (iDNA). The mean amount of eDNA released by each species in the polymicrobial was higher than that in monospecies biofilms (S. aureus: 3.1 × 10

Indexed as

BiofilmsCandida albicansDeoxyribonuclease IDNA, FungalStaphylococcus aureusStreptococcus mutansHumansDeoxyribonuclease IDNA, FungalAntibioticsBiofilmsC. albicansStaphylococcus aureusStreptococcus mutans

Identifiers

PMID39480631
PMCPMC11711860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.