Evidence map›Paper›PMID 39480522›Full record

ArticleCurrent microbiology2024

First-Genome Sequence Data of an Alcaligenes nematophilus Strain EBU-23 Encoding bla Gene Implicated in Acute Childhood Gastroenteritis.

Ebuka Elijah David, Ikechuku Okorie Igwenyi, Ifeanyichukwu Romanus Iroha, Layla Farage Martins, Guillermo Uceda-Campos, Aline Maria da Silva

Abstract read
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Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ebuka Elijah DavidDepartment of Biochemistry, Alex Ekwueme Federal University, Ndufu-Alike, Ikwo, Nigeria. david.ebuka@funai.edu.ng.ORCID http://orcid.org/0000-0001-6903-6392
Ikechuku Okorie IgwenyiDepartment of Biochemistry, Ebonyi State University, Abakaliki, Ebonyi, Nigeria.ORCID http://orcid.org/0000-0002-2056-751X
Ifeanyichukwu Romanus IrohaDepartment of Microbiology, Ebonyi State University, Abakaliki, Ebonyi, Nigeria.ORCID http://orcid.org/0000-0002-8198-3955
Layla Farage MartinsDepartment of Biochemistry, Institute of Chemistry, University of Sao Paulo, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0002-5277-8813
Guillermo Uceda-CamposDepartment of Biochemistry, Institute of Chemistry, University of Sao Paulo, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0002-7563-7917
Aline Maria da SilvaDepartment of Biochemistry, Institute of Chemistry, University of Sao Paulo, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0001-9249-4922

Funding

International Center for Genetic Engineering and Biotechnology S_NGA20-01-1
6 · The paper itself

Abstract

Although an environmental contaminant, Alcaligenes sp. are now increasingly reported in clinical infections. Here, we present a whole-genome sequence of an extended spectrum beta-lactamase (ESBL) Alcaligenes nematophilus strain EBU-23 encoding beta-lactamase, bla gene, isolated from the stool of a hospitalized infant with acute gastroenteritis in a tertiary hospital in Nigeria. Antibiotics susceptibility test revealed that the isolate was resistant to the β-lactams, cephalosporins, and penicillin, β-lactam combination, and the fluoroquinolones. Genomic analysis exposed the presence of a class A beta-lactam hydrolase gene and multiple multidrug efflux permease which may be responsible for the beta-lactamase and multidrug resistance observed with the isolate. To the best our knowledge, we describe the first whole-genome sequence of a multidrug-resistant A. nematophilus implicated in acute childhood gastroenteritis in Nigeria.

Indexed as

AlcaligenesAnti-Bacterial Agentsbeta-LactamasesGastroenteritisGenome, BacterialDrug Resistance, Multiple, BacterialFecesHumansInfantMicrobial Sensitivity TestsNigeriaWhole Genome SequencingAnti-Bacterial Agentsbeta-Lactamases

Identifiers

PMID39480522

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.