Evidence map›Paper›PMID 39480494›Full record

ArticleThe Journal of clinical investigation2024

Leptin signaling maintains autonomic stability during severe influenza infection in mice.

Andrés R Muñoz-Rojas, Adam C Wang, Lisa E Pomeranz, Elizabeth L Reizis, Heather W Stout-Delgado, Ileana C Miranda, Krishnan Rajagopalan, Tadiwanashe Gwatiringa, Roger R Fan, Ahmad A Huda and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of clinical investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. FGF21 acting on the noradrenergic nervous system protects against influenza virus infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Andrés R Muñoz-RojasDepartment of Immunology, Harvard Medical School, Boston, Massachusetts, USA.
Adam C WangLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Lisa E PomeranzLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Elizabeth L ReizisLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Heather W Stout-DelgadoDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Weill Cornell Medicine, New York, New York, USA.
Ileana C MirandaLaboratory of Comparative Pathology, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, and The Rockefeller University, New York, New York, USA.
Krishnan RajagopalanDepartment of Internal Medicine, Division of Pulmonary and Critical Care, UT Southwestern Medical Center, Dallas, Texas, USA.
Tadiwanashe GwatiringaDepartment of Internal Medicine, Division of Pulmonary and Critical Care, UT Southwestern Medical Center, Dallas, Texas, USA.
Roger R FanDepartment of Internal Medicine, Division of Pulmonary and Critical Care, UT Southwestern Medical Center, Dallas, Texas, USA.
Ahmad A HudaLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Neha MaskeyLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Roseline P OlumuyideLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Aryan S PatelDepartment of Internal Medicine, Division of Pulmonary and Critical Care, UT Southwestern Medical Center, Dallas, Texas, USA.
Jeffrey M FriedmanLaboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockefeller University, New York, New York, USA.
Diane MathisDepartment of Immunology, Harvard Medical School, Boston, Massachusetts, USA.
Kartik N RajagopalanDepartment of Internal Medicine, Division of Pulmonary and Critical Care, UT Southwestern Medical Center, Dallas, Texas, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeff G McDonald · 2022 to 2026
$7.4M
Weill Cornell/Rockefeller/Sloan Kettering MST ProgramT32GM152349 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KATHARINE C HSU · 2024 to 2026
$6.6M
Impact of Aging on Oxysterol Regulation of Alveolar Macrophage Function during S. pneumoniaeR01AG079937 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Heather Winona Stout Delgado · 2023 to 2026
$2.6M
NCI NIH HHS P30 CA008748NIA NIH HHS R01 AG079937NIDDK NIH HHS P30 DK127984NIGMS NIH HHS T32 GM152349
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EndocrinologyInfectious diseaseInfluenzaLeptin

Identifiers

PMID39480494
PMCPMC11684820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.