Evidence map›Paper›PMID 39480094›Full record

ArticleApplied and environmental microbiology2024

Development of a

Laura M Alexander, Saima Khalid, Gina M Gallego-Lopez, Theresa J Astmann, Jee-Hwan Oh, Mark Heggen, Phil Huss, Renee Fisher, Amitava Mukherjee, Srivatsan Raman and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Metabolic Engineering of ProbioticFoods (Basel, Switzerland) · 2026
    Article
  2. Revised complete genome sequences ofMicrobiology spectrum · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Laura M AlexanderDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Saima KhalidDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Gina M Gallego-LopezDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-7872-5595
Theresa J AstmannDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jee-Hwan OhDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9033-8539
Mark HeggenDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Phil HussDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Renee FisherDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Amitava MukherjeeDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Srivatsan RamanDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
In Young ChoiDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-3730-5193
Morgan N SmithDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Claude J RogersChromoLogic, LLC, Monrovia, California, USA.
Michael W EpperlyDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Laura J KnollDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-9362-8088
Joel S GreenbergerDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Jan-Peter van PijkerenDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4649-5726

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Development of second-generation probiotics as radiation mitigators75N93021C00008 · NIAID · CHROMOLOGIC, LLC · PI ROGERS, CLAUDE · 2021 to 2024
$2.7M
LR-IL-22 for Mitigation and Management of Radiation InjuriesU01AI172885 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOEL S GREENBERGER · 2023 to 2026
$2.4M
Multi-tiered containment system for engineered microbesR01GM135483 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI VAN PIJKEREN, JAN-PETER · 2020 to 2023
$1.3M
Mitigation of Ionizing Irradiation-Induced Intestinal Damage by Second-Generation Probiotics LR-IL-22 and LR-IFN-βR41AI157357 · NIAID · CHROMOLOGIC, LLC · PI GREENBERGER, JOEL S, ROGERS, CLAUDE J. · 2021 to 2022
$600k
Development of a biological containment strategy for recombinant Lactobacillus reuteriR21AI146634 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI VAN PIJKEREN, JAN-PETER · 2019 to 2020
$426k
Dissertation Completion Fellowship from the UW-Madison Graduate SchoolHHS | National Institutes of Health (NIH) U01-AI172885HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 1R41AI157357-01HHS | NIH | National Institute of General Medical Sciences (NIGMS) R01GM135483Louis and Elsa Thomsen Wisconsin Distinguished Graduate Fellowship from the UW-Madison College of Agricultural & Life SciencesNIAID NIH HHS 75N93021C00008NIAID NIH HHS R21 AI146634NIAID NIH HHS R41 AI157357NIAID NIH HHS U01 AI172885NIGMS NIH HHS R01 GM135483NIGMS NIH HHS T32 GM007215SciMed Graduate Research Scholars Program at UW-MadisonU.S. Department of Agriculture (USDA) 2021-67015-34316UW-Madison Food Research Institute MSN1856150
6 · The paper itself

Abstract

Bacterial biotherapeutic delivery vehicles have the potential to treat a variety of diseases. This approach obviates the need to purify the recombinant effector molecule, allows delivery of therapeutics

Indexed as

Limosilactobacillus reuteriAdhesins, BacterialAnimalsBacterial AdhesionDrug Delivery SystemsFemaleHT29 CellsHumansMiceAdhesins, Bacterialadhesinsbiotherapeuticcolonizationengineered probioticprobiotic

Identifiers

PMID39480094
PMCPMC11577788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.