Evidence map›Paper›PMID 39479861›Full record

ArticleHaematologica2025

Early death and intracranial hemorrhage prediction in acute promyelocytic leukemia: validation of a risk score in a cohort from an international consortium treated with chemotherapy plus all-

Wellington F Silva, Haesook T Kim, Maria S Undurraga, Juan R Navarro-Cabrera, Victor Salinas, Pablo Muxi, Raul A M Melo, Ana Beatriz F Gloria, Katia B B Pagnano, Elenaide C Nunes and 22 more

Registry-linked trialAbstract read
In one paragraph

Article in Haematologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06982274 (Combination of Oral Arsenic With ATRA and Minimal-Dose Chemotherapy for Newly Diagnosed Patients With Acute Promyelocytic Leukemia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06982274 phase2recruitingnot on this map

Combination of Oral Arsenic With ATRA and Minimal-Dose Chemotherapy for Newly Diagnosed Patients With Acute Promyelocytic Leukemia: a Study by the International Consortium on APL

TypeinterventionalSponsorInstituto do Cancer do Estado de São PauloRan2023 to 2029Enrolled115ConditionsAcute Promyelocytic Leukemia (APL)ArmsRealgar-Indigo Naturalis Formulation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Predictors of Early Death in Acute Promyelocytic Leukemia.Medical sciences (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Wellington F SilvaHospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo.
Haesook T KimDana-Farber Cancer Institute, Boston.
Maria S UndurragaHospital del Salvador, Providencia, Chile.
Juan R Navarro-CabreraEdgardo Rebagliati Hospital, Jesus Maria, Peru.
Victor SalinasInstituto de Prevision Social, Asuncion, Paraguay.
Pablo MuxiHospital Britanico, Montevideo, Uruguay.
Raul A M MeloUniversity of Pernambuco, Recife.
Ana Beatriz F GloriaFederal University of Minas Gerais, Belo Horizonte.
Katia B B PagnanoUniversidade Estadual de Campinas, Campinas.
Elenaide C NunesFederal University of Parana, Curitiba.
Rosane Isabel BittencourtHospital de Clinicas de Porto Alegre, Porto Alegre.
Ninoska RojasEdgardo Rebagliati Hospital, Jesus Maria, Peru.
Shirley M Q TruyenqueInstituto Nacional de Enfermedades Neoplasicas, Surquillo, Peru.
Ana Ilda Ayala-LugoUniversidad Nacional de Asuncion, Asuncion, Paraguay.
Ana Carolina OliverHospital Britanico, Montevideo, Uruguay.
Lorena L Figueiredo-PontesRibeirao Preto Medical School, Ribeirao Preto.
Fabiola TrainaRibeirao Preto Medical School, Ribeirao Preto.
Frederico MoreiraHospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo.
Evandro M FagundesFederal University of Minas Gerais, Belo Horizonte.
Bruno K L DuarteUniversidade Estadual de Campinas, Campinas.
Analí Pamela Mora-AlferezInstituto Nacional de Enfermedades Neoplasicas, Surquillo, Peru.
Percy OrtizEdgardo Rebagliati Hospital, Jesus Maria, Peru.
Jose Luis UntamaEdgardo Rebagliati Hospital, Jesus Maria, Peru.
Martin S TallmanMemorial Sloan Kettering Cancer Center, New York.
Raul C RibeiroSt. Jude Children's Research Hospital, Memphis.
Arnold GanserHannover Medical School, Hannover.
Richard James DillonKing's College, London.
Peter J M ValkErasmus University Medical Center, Rotterdam.
Miguel A SanzValencia University Medical School, Valencia.
Bob LöwenbergErasmus University Medical Center, Rotterdam.
Nancy BerlinerBrigham and Women's Hospital, Boston.
Eduardo M RegoHospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo. eduardo.rego@hc.fm.usp.br.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39479861
PMCPMC11873706

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.