Evidence map›Paper›PMID 39479712›Full record

ArticleFood science & nutrition2024

Assessment of the anti-inflammatory and anti-glycemic properties of Royal Jelly and Tocotrienol-rich fraction in an experimental study: Does irisin mediate these effects?

Naimeh Mesri Alamdari, Pardis Irandoost, Neda Roshanravan, Farzad Najafipour, Mohammadreza Vafa, Farnaz Farsi, Majid Mobasseri, Amir Ali Mir Mazhari, Halimeh AmirAzad, Farzad Shidfar

Abstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Naimeh Mesri AlamdariEndocrine Research Center Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0003-2563-8193
Pardis IrandoostDepartment of Nutrition, School of Public Health Iran University of Medical Sciences Tehran Iran.
Neda RoshanravanCardiovascular Research Center Tabriz University of Medical Sciences Tabriz Iran.
Farzad NajafipourEndocrine Research Center Tabriz University of Medical Sciences Tabriz Iran.
Mohammadreza VafaDepartment of Nutrition, School of Public Health Iran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0001-7052-8810
Farnaz FarsiMinimally Invasive Surgery Research Center Iran University of Medical Sciences Tehran Iran.
Majid MobasseriEndocrine Research Center Tabriz University of Medical Sciences Tabriz Iran.
Amir Ali Mir MazhariDepartment of Laboratory Sciences, Faculty of Para Medicine Tabriz University of Medical Sciences Tabriz Iran.
Halimeh AmirAzadEndocrine Research Center Tabriz University of Medical Sciences Tabriz Iran.
Farzad ShidfarDepartment of Nutrition, School of Public Health Iran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-6531-9253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irisin, a novel adipomyokine, has been proposed to be a therapeutic agent against obesity-related metabolic disease. Royal Jelly (RJ) and tocotrienol-rich fraction (TRF) are suggested to promote obesity and its related problems through potential mutual mechanistic pathways. This investigation intended to evaluate the glycemic and inflammation-promoting effects of RJ, TRF, and their combinations to evaluate their synergic effects through irisin action in obese rats induced by a high-fat diet (HFD) that underwent a calorie restriction diet (CRD). Fifty HFD-fed obese rats received the following interventions: RJ, TRF, or RJ + TRF in combination with a CRD for eight consecutive weeks. After the investigation, body weight, fasting blood sugar (FBS), irisin, insulin, C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1 beta (IL-1β), leptin, adiponectin, and insulin resistance (IR) were assessed. After 8 weeks of treatment, significant weight reduction was noticed in rats that received RJ and RJ + TRF related to the CRD rats (

Indexed as

glucose hemostasisinflammationirisinobesityRoyal Jellytocotrienol‐rich fraction

Identifiers

PMID39479712
PMCPMC11521737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.