Evidence map›Paper›PMID 39479525›Full record

ArticleFrontiers in cellular neuroscience2024

Arid3c identifies an uncharacterized subpopulation of V2 interneurons during embryonic spinal cord development.

Estelle Renaux, Charlotte Baudouin, Olivier Schakman, Ondine Gay, Manon Martin, Damien Marchese, Younès Achouri, René Rezsohazy, Françoise Gofflot, Frédéric Clotman

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In one paragraph

Article in Frontiers in cellular neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Estelle RenauxUniversité catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, Animal Molecular and Cellular Biology group, Louvain-la-Neuve, Belgium.
Charlotte BaudouinUniversité catholique de Louvain, Institute of Neuroscience, Laboratory of Neural Differentiation, Brussels, Belgium.
Olivier SchakmanUniversité catholique de Louvain, Institute of Neuroscience, Behavioral Analysis Platform (BEAP), Brussels, Belgium.
Ondine GayMaster de Biologie, École Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Université de Lyon, Lyon Cedex, France.
Manon MartinUniversité catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, Louvain-la-Neuve, Belgium.
Damien MarcheseUniversité catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, Animal Molecular and Cellular Biology group, Louvain-la-Neuve, Belgium.
Younès AchouriUniversité catholique de Louvain, de Duve Institute, Transgenic Core Facility, Brussels, Belgium.
René RezsohazyUniversité catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, Animal Molecular and Cellular Biology group, Louvain-la-Neuve, Belgium.
Françoise GofflotUniversité catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, Animal Molecular and Cellular Biology group, Louvain-la-Neuve, Belgium.
Frédéric ClotmanUniversité catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, Animal Molecular and Cellular Biology group, Louvain-la-Neuve, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motor activity is organized by neuronal networks composed of motor neurons and a wide variety of pre-motor interneuron populations located in the brainstem and spinal cord. Differential expression and single-cell RNA sequencing studies recently unveiled that these populations subdivide into multiple subsets. However, some interneuron subsets have not been described yet, and the mechanisms contributing to this neuronal diversification have only been partly deciphered. In this study, we aimed to identify additional markers to further describe the diversity of spinal V2 interneuron populations. Here, we compared the transcriptome of V2 interneurons with that of the other cells of the embryonic spinal cord and extracted a list of genes enriched in V2 interneurons, including

Indexed as

Arid3cembryonic spinal cordmotor activitymotor circuitsV2c interneuronsV2 interneurons

Identifiers

PMID39479525
PMCPMC11521906

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.