Evidence map›Paper›PMID 39479454›Full record

ArticleTheranostics2024

DNASE1L3-mediated PANoptosis enhances the efficacy of combination therapy for advanced hepatocellular carcinoma.

Jingchun Wang, Yu Chen, Yanquan Xu, Jiangang Zhang, Shuai Yang, Yu Zhou, Juan Lei, Ran Ren, Yang Chen, Huakan Zhao and 2 more

Abstract read
In one paragraph

Article in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. PANoptosis and Immune Remodeling in the Tumor Microenvironment.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Oncology research · 2026
    Article
  15. Review
  16. PANoptosis: potential new targets and therapeutic prospects in digestive diseases.Apoptosis : an international journal on programmed cell death · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jingchun WangDepartment of Gastroenterology, Second Affiliated Hospital, Army Medical University; Chongqing 400037, China.
Yu ChenDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Yanquan XuClinical Medicine Research Center, Second Affiliated Hospital, Army Medical University; Chongqing 400037, China.
Jiangang ZhangDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Shuai YangDepartment of Pathology, First Affiliated Hospital, Army Medical University; Chongqing 400037, China.
Yu ZhouDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Juan LeiDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Ran RenDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Yang ChenDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Huakan ZhaoDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Yongsheng LiDepartment of Medical Oncology, Chongqing University Cancer Hospital; Chongqing 400030, China.
Shiming YangDepartment of Gastroenterology, Second Affiliated Hospital, Army Medical University; Chongqing 400037, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, HepatocellularEndodeoxyribonucleasesLiver NeoplasmsSorafenibAnimalsAntineoplastic Combined Chemotherapy ProtocolsApoptosisCell Line, TumorFemaleHumansImmune Checkpoint InhibitorsMaleMiceProgrammed Cell Death 1 ReceptorProteomicsXenograft Model Antitumor AssaysDNASE1L3 protein, humanEndodeoxyribonucleasesImmune Checkpoint InhibitorsPDCD1 protein, humanProgrammed Cell Death 1 ReceptorSorafenibadvanced hepatocellular carcinomacombination therapyDNASE1L3PANoptosis

Identifiers

PMID39479454
PMCPMC11519790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.