Evidence map›Paper›PMID 39479244›Full record

ArticleRoyal Society open science2024

Milk metabolite composition of a semi-captive population of Asian elephants.

Laura Galante, Diogo João Franco Dos Santos, Elisabeth Mikkonen, Jeannie Horak, Zorica Stijepic, Hans Demmelmair, Andrea Vielhauer, Berthold Koletzko, Htet Thi Zaw, Win Htut and 2 more

Abstract read
In one paragraph

Article in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura GalanteSchool of Medicine, Swansea University, Swansea SA2 8PP, UK.ORCID https://orcid.org/0000-0002-6190-7955
Diogo João Franco Dos SantosDepartment of Biology, University of Turku, Turku FI-20014, Finland.
Elisabeth MikkonenDepartment of Biology, University of Turku, Turku FI-20014, Finland.ORCID https://orcid.org/0009-0002-9133-6855
Jeannie HorakDepartment of Metabolic and Nutritional Medicine, Ludwig-Maximilians-University Munich, Medical Center, Munich D-80337, Germany.
Zorica StijepicDepartment of Metabolic and Nutritional Medicine, Ludwig-Maximilians-University Munich, Medical Center, Munich D-80337, Germany.
Hans DemmelmairDepartment of Metabolic and Nutritional Medicine, Ludwig-Maximilians-University Munich, Medical Center, Munich D-80337, Germany.
Andrea VielhauerDepartment of Metabolic and Nutritional Medicine, Ludwig-Maximilians-University Munich, Medical Center, Munich D-80337, Germany.
Berthold KoletzkoDepartment of Metabolic and Nutritional Medicine, Ludwig-Maximilians-University Munich, Medical Center, Munich D-80337, Germany.
Htet Thi ZawMyanma Timber Enterprise, Yangon 11011, Myanmar.
Win HtutMyanma Timber Enterprise, Yangon 11011, Myanmar.
Virpi LummaaDepartment of Biology, University of Turku, Turku FI-20014, Finland.
Mirkka LahdenperäDepartment of Biology, University of Turku, Turku FI-20014, Finland.ORCID https://orcid.org/0000-0003-0062-6284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lack of maternal milk commonly leads to Asian elephant calves' death in captivity. Currently, available supplements seem inefficient. Hence, we aimed at characterizing the composition of Asian elephant milk to provide information on calves' nutritional needs. Seventy milk samples from 22 Asian elephants living in semi-captivity in their natural environment in Myanmar were collected. Samples were analysed through various techniques including liquid chromatography tandem mass spectrometry, gas chromatography-flame ionization detector, and bicinchoninic acid assay to determine total protein content and various metabolites. Associations with lactation stage (months postpartum) were investigated through repeated measure mixed models. We identified 160 compounds: 22 amino acids, 12 organic acids of the tricarboxylic acid cycle, 27 fatty acids, 15 acyl-carnitines and 84 phospholipids. The milk contained substantial amounts of free glutamate (median: 1727.9, interquartile range (IQR): 1278.4 µmol l

Indexed as

animal nutritionElephas maximuslactation physiologymilk compositionmilk metabolome

Identifiers

PMID39479244
PMCPMC11522882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.