Evidence map›Paper›PMID 39479223›Full record

ArticleRespirology case reports2024

Novel CYCLIN-O pathogenic variants in a patient presenting with bronchiectasis secondary to reduced generation of multiple motile cilia.

Kim Hoong Yap, Albert Yick Hou Lim, Biju Thomas, Carine Bonnard, Emmanuelle Szenker-Ravi, Yan Ling Chong, Sudipto Roy, Bruno Reversade

Abstract read
In one paragraph

Article in Respirology case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kim Hoong YapDepartment of Respiratory & Critical Care Medicine Tan Tock Seng Hospital Singapore.ORCID https://orcid.org/0009-0006-7082-9246
Albert Yick Hou LimDepartment of Respiratory & Critical Care Medicine Tan Tock Seng Hospital Singapore.
Biju ThomasDepartment of Paediatric Respiratory Medicine KK Women's and Children's Hospital Singapore.
Carine BonnardModel Development, A*STAR Skin Research Labs (A*SRL) Agency for Science, Technology and Research (A*STAR) Singapore.
Emmanuelle Szenker-RaviLaboratory of Human Genetics & Therapeutics, Center of Excellence for Smart Health, BESE King Abdullah University of Science and Technology (KAUST) Thuwal Saudi Arabia.
Yan Ling ChongInstitute of Molecular and Cell Biology (IMCB) Agency for Science, Technology and Research (A*STAR) Proteos Singapore.
Sudipto RoyInstitute of Molecular and Cell Biology (IMCB) Agency for Science, Technology and Research (A*STAR) Proteos Singapore.
Bruno ReversadeLaboratory of Human Genetics & Therapeutics, Center of Excellence for Smart Health, BESE King Abdullah University of Science and Technology (KAUST) Thuwal Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduced generation of multiple motile cilia (RGMC) represents a rare variant of Primary Ciliary Dyskinesia (PCD), associated with

Indexed as

bronchiectasisCCNOmucociliary disorderprimary ciliary dyskinesiaRGMC

Identifiers

PMID39479223
PMCPMC11519382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.