Evidence map›Paper›PMID 39479129›Full record

ReviewCureus2024

Efficacy and Safety of Mometasone Furoate Nasal Spray in Treating Nasal Polyposis: A Systematic Review and Meta-Analysis.

Osamah H Mohya, Alaa A Alghamdi, Alanoud A Alomar, Amal M Alharbi, Amal M Ageeli, Danah H Alharbi, Haya M Alotaibi, Manar S Alghamdi, Marya A Alkhamis, Moath H Shawosh and 5 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Osamah H MohyaMedicine and Surgery, Faculty of Medicine, King Khalid University, Abha, SAU.
Alaa A AlghamdiMedicine and Surgery, Faculty of Medicine, Umm Al-Qura University, Makkah, SAU.
Alanoud A AlomarMedicine and Surgery, Faculty of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, SAU.
Amal M AlharbiMedicine and Surgery, Faculty of Medicine, King Faisal University, Alhasa, SAU.
Amal M AgeeliMedicine and Surgery, Faculty of Medicine, Jazan University, Jazan, SAU.
Danah H AlharbiMedicine and Surgery, Faculty of Medicine, Umm Al-Qura University, Makkah, SAU.
Haya M AlotaibiMedicine and Surgery, Faculty of Medicine, Taif University, Taif, SAU.
Manar S AlghamdiMedicine and Surgery, Faculty of Medicine, University of Jeddah, Jeddah, SAU.
Marya A AlkhamisMedicine and Surgery, Faculty of Medicine, king Faisal University, Alhasa, SAU.
Moath H ShawoshMedicine and Surgery, Faculty of Medicine, University of Jeddah, Jeddah, SAU.
Renad S AlayidhMedicine and Surgery, Faculty of Medicine, King Saud University, Riyadh, SAU.
Salma A BinmahfoodhMedicine and Surgery, Faculty of Medicine, Umm Al-Qura University, Makkah, SAU.
Shahad M AlbariqiMedicine and Surgery, Faculty of Medicine, King Khalid University, Abha, SAU.
Hadi Afandi Al-HakamiOtolaryngology, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU.
Mohammed Al-GarniOtolaryngology-Head and Neck Surgery, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Topical and systemic corticosteroids are the most effective medical treatment for nasal polyps, this study aims to systematically explore the efficacy and safety of mometasone furoate (MTF) for patients with nasal polyps (NP). The systematic review was conducted following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines and was registered in The International Prospective Register of Systematic Reviews (PROSPERO.) Data were extracted from relevant and appropriate randomized controlled trials (RCTs) of synthetic corticosteroids for patients with nasal polyps from PubMed, Google Scholar, Web of Science, and Science Direct, encompassing studies published between January 1995 and July 2024. A total of 834 publications were found based on the search criteria. Around 1,710 patients were reviewed for this systematic review from full full-text articles. Primary outcomes include a change in polyp size (assessed by total polyp size scores), and nasal congestion (assessed by measuring changes from baseline in nasal congestion/obstruction scores). secondary outcomes consist of nasal symptoms, including loss of smell, anterior rhinorrhea, postnasal drip, quality of life outcomes, and adverse events. Mometasone furoate nasal spray (MFNS) significantly improves nasal symptoms and reduces nasal polyp size for patients with nasal polyps (NP).

Indexed as

efficacymometasone furoatenasal polypsrandomized controlled trialssafety

Identifiers

PMID39479129
PMCPMC11523191

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.