Evidence map›Paper›PMID 39479083›Full record

ArticleCureus2024

Enhanced Creatinine Level in Diabetic Patients Maximizing the Possibilities of Nephropathy and Its Association With Blood Urea Nitrogen and Glomerular Filtration Rate.

Batool Butt, Bushra Ghulam, Zahira Bashir, Sajid Rafique Abbasi, Shoukat Hussain, Sarosh Khan Jadoon, Amna Akbar, Mumtaz Ahmad Khan

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Batool ButtNephrology, Foundation University School of Health Sciences, Rawalpindi, PAK.
Bushra GhulamBiochemistry, Islamic International Medical College, Rawalpindi, PAK.
Zahira BashirBiochemistry, Mohi-ud-Din Islamic Medical College AJK, Mirpur, PAK.
Sajid Rafique AbbasiNephrology, Pakistan Institute of Medical Sciences, Islamabad, PAK.
Shoukat HussainMedicine/Endocrinology, Capital Development Authority (CDA) Hospital, Islamabad, PAK.
Sarosh Khan JadoonGeneral Surgery, Combined Military Hospital, Muzaffarabad, PAK.
Amna AkbarSurgery, District Headquarter Hospital, Muzaffarabad, PAK.
Mumtaz Ahmad KhanPathology, Abbas Institute of Medical Sciences, Muzaffarabad, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiabetes mellitus is a common metabolic disorder that is sometimes responsible for kidney diseases, especially in the form of diabetic nephropathy. In this study, we tried to investigate the markers associated with kidney diseases within diabetic patients as compared to non-diabetic participants. METHODOLOGY: In this study, among 237 participants, 81 patients were diabetic, whereas 156 were non-diabetic participants. The level and association of serum creatinine, blood urea nitrogen (BUN), and glomerular filtration rate (GFR) were investigated using the enzymatic method and CKD-EPI equation respectively.

resultWe found significantly higher creatinine and BUN levels and lower GFR in the diabetic group compared to the non-diabetic group. Besides, we determined a positive association between creatinine and BUN, and an inverse relationship between GFR and creatinine and BUN respectively which was highly scattered in the case as compared to the non-diabetic group. Further analysis of the participants with high creatinine levels only supported the main outcomes.  Conclusion: Our investigation of kidney markers suggests a significant association between diabetes and kidney complications. Leading a healthy lifestyle and maintaining blood sugar and pressure may help to slow down the progress of diabetic nephropathy for diabetic patients.

Indexed as

diabeticglomerulikidneynephropathynitrogenous wasterenal

Identifiers

PMID39479083
PMCPMC11522845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.