Evidence map›Paper›PMID 39478972›Full record

ArticleInternational medical case reports journal2024

Influence of Placenta Extract Intake on Periodontal Diseases and Oral Environment: A Case Series.

Hizuru Miyamoto, Kentarou Tahara, Eiichi Hirano

Abstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hizuru MiyamotoDentistry and Oral Surgery of Happy Town, Shiki, Saitama, Japan.
Kentarou TaharaMedical Affairs Department, Japan Bio Products, Co., Ltd., Shibuya, Tokyo, Japan.
Eiichi HiranoMedical Affairs Department, Japan Bio Products, Co., Ltd., Shibuya, Tokyo, Japan.ORCID 0000-0002-8607-1488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The placenta extract is used as a dietary supplement. We aimed to investigate the effects of placenta extract on periodontal disease. Case Presentation: In this study, placenta extract supplements were found to improve the oral environment of young and middle-aged Japanese women undergoing maintenance; after three months of taking placenta extract, bleeding upon probing was reduced. In addition, two parameters, white blood cells and protein, improved in the SillHa test, suggesting that the placenta extract contributes to the reduction of gingival inflammation through its anti-inflammatory effect. No adverse events were observed with the placenta extract. Conclusion: Placenta extract may lead to better management, including oral rehabilitation and pharmacotherapy. However, its effect on gingival inflammation requires further investigation in a larger number of cases.

Indexed as

bleeding on probingdentistrygingivitisperiodontologyplacenta extractSillHa

Identifiers

PMID39478972
PMCPMC11523937

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.