Evidence map›Paper›PMID 39478855›Full record

ArticleFrontiers in immunology2024

Dectin-1 participates in the immune-inflammatory response to mouse

Liu Guibo, Dong Chunxu, Chen Biao, Hu Zhaolei, Liu Wenwen, Ji Xiangnan, Peng Wentao, Chang Hongmin, Li Yonghua, Zhu Guoqiang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Synthetic Ligands of Myeloid C-Type Lectin Receptors.Chembiochem : a European journal of chemical biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liu GuiboDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Dong ChunxuDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Chen BiaoDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Hu ZhaoleiDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Liu WenwenDepartment of Ophthalmology, Jiaozhou Central Hospital, Qingdao, Shandong, China.
Ji XiangnanDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Peng WentaoDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Chang HongminDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Li YonghuaDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Zhu GuoqiangDepartment of Ophthalmology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The aim of this study was to investigate whether Dectin-1 influences the immune-inflammatory response in Methods: 1. The models of 1-day, 3-day, and 5-day of fungal keratitis were established in SPF C57BL/6 mice after stimulation by Results: 1. With curdlan pre-treatment, mouse corneal inflammation worsened, and the clinical score increased after infection. In contrast, in the laminaran pre-treated group, corneal inflammation was alleviated and the clinical score decreased significantly compared to the PBS group after infection. 2. Compared with the control group, the expression levels of macrophage phenotype-related M1 and M2 cytokine mRNAs increased significantly 1, 3, and 5 days after Conclusion: In a mouse model of

Indexed as

AspergillosisAspergillus fumigatusCytokinesKeratitisLectins, C-TypeMacrophagesAnimalsbeta-GlucansDectin-1Disease Models, AnimalFemaleMacrophage ActivationMiceMice, Inbred C57BLRAW 264.7 Cellsbeta-GlucanscurdlanCytokinesDectin-1Lectins, C-Typedectin-1fungal keratitisinnate immune responsemacrophagepolarization

Identifiers

PMID39478855
PMCPMC11523060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.