Evidence map›Paper›PMID 39478782›Full record

ReviewJournal of clinical and translational science2024

Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future.

Stacey J Adam, Timothy G Buchman, Judith S Currier, Ruxandra Draghia-Akli, Josh P Fessel, Elizabeth S Higgs, Eric A Hughes, Lisa LaVange, Joseph P Menetski, Sarah W Read and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical and translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stacey J AdamFoundation for the National Institutes of Health, North Bethesda, MD, USA.ORCID https://orcid.org/0000-0002-4590-5175
Timothy G BuchmanCritical Care Center, Emory University School of Medicine, Atlanta, GA, USA.
Judith S CurrierDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Ruxandra Draghia-AkliThe Janssen Pharmaceutical Companies of Johnson & Johnson, Titusville, NJ, USA.
Josh P FesselNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Elizabeth S HiggsNational Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.
Eric A HughesTeva Pharmaceuticals, Parsippany, NJ, USA.
Lisa LaVangeBiostatistics, Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, NC, USA.
Joseph P MenetskiFoundation for the National Institutes of Health, North Bethesda, MD, USA.
Sarah W ReadNational Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0003-3876-472X
Yves RosenbergNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Randall TresslerNational Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.
ACTIV Therapeutics-Clinical Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Accelerating COVID-19 Therapeutic Interventions and Vaccines Therapeutic-Clinical Working Group members gathered critical recommendations in follow-up to lessons learned manuscripts released earlier in the COVID-19 pandemic. Lessons around agent prioritization, preclinical therapeutics testing, master protocol design and implementation, drug manufacturing and supply, data sharing, and public-private partnership value are shared to inform responses to future pandemics.

Indexed as

Covid-19lessons learnedmaster protocoltherapeuticstrials

Identifiers

PMID39478782
PMCPMC11523022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.