ArticleFrontiers in aging neuroscience2024
Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study.
Article in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The Effect of Single Pulse TMS on Working Memory Performance: An Online TMS And fNIRS Study.medRxiv : the preprint server for health sciences · 2026Article
- Transcutaneous auricular vagus nerve stimulation during a 3-back task: a high-density functional near-infrared spectroscopy study.Experimental brain research · 2026Article
- Association of Malaysian-MIND Diet Scores with Brain Activation in Older Adults: A Functional MRI Study.Biomedicines · 2026Article
- MGFNet: A Multi-Granularity Fusion Network with Coupling-Guided Sparse Routing for Hybrid EEG-fNIRS Decoding.Sensors (Basel, Switzerland) · 2026Article
- Cortical activation, gait performance, and muscle activation during dual-task walking in older adults with mild cognitive impairment.BMC geriatrics · 2026Article
- Research progress on exercise-induced executive function improvements in older adults: insights from functional near-infrared spectroscopy.Frontiers in psychology · 2026Review
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- The impact of smartphone use on working memory in college students: a functional near-infrared spectroscopy study.Frontiers in psychiatry · 2025Article
- Associations between declines in uneven terrain walking speed and visuospatial working memory in older adults.Frontiers in aging neuroscience · 2025Article
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: The n-back task is a widely used paradigm to assess working memory and is commonly applied in research on age-related cognitive decline. However, studies utilizing functional near-infrared spectroscopy (fNIRS) to explore this area are limited. Objective: This study aims to investigate age-related differences in brain activation during the n-back task using fNIRS. Methods: fNIRS data were collected from 18 elderly and 19 young participants while performing different n-back tasks. Brain activation patterns and peripheral performance were compared between the two groups. Results: Significant differences in brain activation patterns were observed between elderly and young participants. Under the 3-back condition, the older group exhibited reduced activation in brain regions adjacent to prefrontal cognitive areas compared to the younger group. Additionally, the older group's performance plateaued at the 2-back level, along with a decline in prefrontal activation. Conclusion: These findings may suggest potential markers for cognitive decline, providing a new target for future screening.
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