Evidence map›Paper›PMID 39478594›Full record

ArticleEnvironmental health : a global access science source2024

Prenatal exposure to air pollution during the early and middle stages of pregnancy is associated with adverse neurodevelopmental outcomes at ages 1 to 3 years.

Frederica Perera, Yuqi Miao, Zev Ross, Virginia Rauh, Amy Margolis, Lori Hoepner, Kylie W Riley, Julie Herbstman, Shuang Wang

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Gestational exposure to PMEnvironmental epidemiology (Philadelphia, Pa.) · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Frederica PereraMailman School of Public Health, Columbia Center for Children's Environmental Health, Columbia University, New York, NY, USA. fpp1@columbia.edu.
Yuqi MiaoDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Zev RossZev Ross Spatial Analysis, Ithaca, NY, USA.
Virginia RauhHeilbrunn Department of Population and Family Health, Mailman School of Public Health, Columbia University, New York, NY, USA.
Amy MargolisDepartment of Psychiatry, Columbia University Irving Medical Center, Columbia University, New York, NY, USA.
Lori HoepnerData Coordinating Center, Mailman School of Public Health, Columbia University, New York, NY, USA.
Kylie W RileyMailman School of Public Health, Columbia Center for Children's Environmental Health, Columbia University, New York, NY, USA.
Julie HerbstmanMailman School of Public Health, Columbia Center for Children's Environmental Health, Columbia University, New York, NY, USA.
Shuang WangDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.

Funding

Not whether but how: The ethics of reporting individual results in a pregnancy cohort.UH3OD023290 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Julie Beth Herbstman, AMY MARGOLIS · 2018 to 2026
$18.8M
HEALTH EFFECTS OF PAH &ETS IN MINORITY WOMEN &NEWBORNSR01ES008977 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PERERA, FREDERICA P · 1997 to 2011
$12.9M
Identifying Newborns at Risk of Adverse Neurodevelopmental Outcomes and Obesity from Air Pollution.UG3OD023290 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERBSTMAN, JULIE BETH, MARGOLIS, AMY · 2016 to 2024
$10.9M
Urban Diesel Exposure and Inner City AsthmaR01ES013163 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, RACHEL L · 2005 to 2016
$6.5M
Phthalate Exposure and Inner City Pediatric AsthmaR01ES014393 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WHYATT, ROBIN MARJORIE · 2007 to 2011
$3.1M
To Maintain and Enrich Resource Infrastructure for Existing Environmental Epidemiology CohortsR24ES029489 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Julie Beth Herbstman, Marcela Tamayo-Ortiz · 2020 to 2026
$2.3M
Early-life bisphenol A, immune dysregulation, and inner-city pediatric asthmaRC2ES018784 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WHYATT, ROBIN MARJORIE · 2009 to 2010
$1.4M
NIEHS NIH HHS R01 ES008977NIEHS NIH HHS R01 ES013163NIEHS NIH HHS R01 ES014393NIEHS NIH HHS R24 ES029489NIEHS NIH HHS RC2 ES018784NIH HHS UG3 OD023290NIH HHS UH3 OD023290
6 · The paper itself

Abstract

backgroundA large body of data shows that fetal brain development is vulnerable to disruption by air pollution experienced by the mother during pregnancy, adversely affecting cognitive and psychomotor capabilities during childhood (De Asis-Cruz et al., Biol Psychiatry 7:480-90, 2022; Morgan ZEM et al., Environ Health 22:11, 2023). This study has sought to identify gestational windows of susceptibility to prenatal exposure to air pollution.

methods470 African American and Latina mother/child pairs participated in a prospective cohort study based in the low-income communities of Northern Manhattan and the South Bronx, New York City. Gestational exposure to respirable particulate matter (PM

resultsBy linear regression, average exposures to NO

conclusionsOur finding that prenatal exposure to air pollution in the first and second trimesters was associated with lower scores for cognitive development at ages 1 and 3 is of concern because of the potential consequences of these outcomes for long-term functioning. They underscore the need for stronger policies to protect pregnant individuals and offspring, particularly during vulnerable, early life-stage of development.

Indexed as

Air PollutantsAir PollutionMaternal ExposureNitrogen DioxideParticulate MatterPrenatal Exposure Delayed EffectsAdultBlack or African AmericanChild DevelopmentChild, PreschoolFemaleHispanic or LatinoHumansInfantMaleNeurodevelopmental DisordersAir PollutantsNitrogen DioxideParticulate MatterAir pollutionChildrenCritical windowsNeurodevelopmentPrenatal

Identifiers

PMID39478594
PMCPMC11526525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.