Evidence map›Paper›PMID 39478485›Full record

Trial reportBMC anesthesiology2024

Efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy: a prospective, randomized, double-blind controlled clinical trial.

Lizhu Xiao, Zhenghua Zhang, Jing Lu, Zhaoguo Liu, Jiaoling Zhang, Lu Kang, Jiefu Tang, Xiaohua Zou

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lizhu XiaoDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China.
Zhenghua ZhangDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China.
Jing LuDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China.
Zhaoguo LiuDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China.
Jiaoling ZhangDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China.
Lu KangDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China.
Jiefu TangDepartment of Anesthesiology, First Affiliated Hospital of Hunan University of Medicine, Huaihua City, Hunan Province, China. tangjiefu@126.com.
Xiaohua ZouDepartment of Anesthesiology, Affiliated Hospital of Guizhou Medical University, Guiyang City, Guizhou Province, China. zouxiaohuazxh@163.com.

Funding

Department of Science and Technology of Hunan Province,China 2021SK4047Department Science and Technology of Huaihua,China 2022R2203
6 · The paper itself

Abstract

backgroundWe explored the efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy.

methodsA total of 195 patients who underwent painless colonoscopy surgery were randomly divided into three groups: the propofol deep sedation group (group DS), the sufentanil combined with propofol for conscious sedation (group CS

resultsThe incidence of intraoperative hypoxemia in the DS group was significantly greater than that in the CS

conclusionsIn conclusion, esketamine combined with propofol for conscious sedation can be safely and effectively used for painless colonoscopy and has fewer complications.It is recommended for painless colonoscopy.

Indexed as

ColonoscopyKetamineProcedural SedationPropofolAdultAgedDouble-Blind MethodDrug Therapy, CombinationFemaleHumansHypnotics and SedativesMaleMiddle AgedPostoperative Nausea and VomitingProspective StudiesSufentanilEsketamineHypnotics and SedativesKetaminePropofolSufentanilConscious sedationDeep sedationEfficacyEsketaminePainless colonoscopySafety

Identifiers

PMID39478485
PMCPMC11523800

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.