Evidence map›Paper›PMID 39478461›Full record

ArticleBMC geriatrics2024

Analgesic regimens administered to older adults receiving skilled nursing facility care following hip fracture: a proof-of-concept federated analysis.

Andrew R Zullo, Melissa R Riester, Kaleen N Hayes, Yuan Zhang, Sarah D Berry, Emmanuelle Belanger, Meghan A Cupp, Francesca L Beaudoin

Abstract read
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Longitudinal Pain Medication Use Among US Older Adults After a Hip Fracture.Journal of the American Medical Directors Association · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew R ZulloDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA. Andrew_Zullo@brown.edu.
Melissa R RiesterDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA.
Kaleen N HayesDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Yuan ZhangCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, RI, USA.
Sarah D BerryHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, USA.
Emmanuelle BelangerDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Meghan A CuppDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA.
Francesca L BeaudoinDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA.

Funding

Clinically Significant Drug Interactions among Nursing Home Residents with ADRDR01AG077620 · NIA · BROWN UNIVERSITY · PI Andrew Reis Zullo · 2022 to 2026
$3.5M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Opioid use in post-acute hip fracture care: prescribing patterns, effectiveness, and safetyR21AG061632 · NIA · BROWN UNIVERSITY · PI BEAUDOIN, FRANCESCA, ZULLO, ANDREW REIS · 2019 to 2020
$462k
NIA NIH HHS R01 AG065722NIA NIH HHS R01 AG077620NIA NIH HHS R21 AG061632
6 · The paper itself

Abstract

backgroundAlthough a majority of patients in the U.S. receive post-acute care in skilled nursing facilities (SNFs) following hip fracture, large-sample observational studies of analgesic prescribing and use in SNFs have not been possible due to limitations in available data sources. We conducted a proof-of-concept federated analysis of electronic health records (EHRs) from 11 SNF chains to describe analgesic use during hip fracture post-acute care.

methodsWe included residents with a diagnosis of hip fracture between January 1, 2018 and June 30, 2021 who had at least one administration of an analgesic. Use of analgesics was ascertained from EHR medication orders and medication administration records. We quantified the proportion of residents receiving analgesic regimens based on the medications that were administered up to 100 days after hip fracture diagnosis. Plots visualizing trends in analgesic use were stratified by multiple resident characteristics including age and Alzheimer's Disease and Related Dementias (ADRD) diagnosis.

resultsThe study included 23,706 residents (mean age 80.5 years, 68.6% female, 87.7% White). Most (~ 60%) residents received opioids + APAP. Monotherapy with APAP or opioids was also common. The most prevalent regimens were oxycodone + APAP (20.1%), hydrocodone + APAP (15.8%), APAP only (15.1%), tramadol + APAP (10.4%), and oxycodone only (4.3%). During the study period, use of APAP-only increased, opioids-only decreased, and opioids + APAP remained stable. Use of APAP-only appeared to be more prevalent among individuals aged > 75 years (versus ≤ 75 years) and those with ADRD (versus without).

conclusionsWe successfully leveraged federated SNF EHR data to describe analgesic use among residents receiving hip fracture post-acute care.

Indexed as

AnalgesicsHip FracturesSkilled Nursing FacilitiesAgedAged, 80 and overElectronic Health RecordsFemaleHumansMalePain ManagementProof of Concept StudyUnited StatesAnalgesicsAnti-Inflammatory AgentsElectronic Health RecordsNon-SteroidalOpioidRehabilitation

Identifiers

PMID39478461
PMCPMC11523817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.