Evidence map›Paper›PMID 39478092›Full record

ArticleScientific reports2024

AI predictive modeling of survival outcomes for renal cancer patients undergoing targeted therapy.

Yaoqi Yu, Jirui Niu, Yin Yu, Silong Xia, Shiheng Sun

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaoqi Yu *Department of Urology, Heilongjiang Provincial Hospital, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin, 150036, China.
Jirui Niu *Department of Urology, Heilongjiang Provincial Hospital, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin, 150036, China.
Yin YuDepartment of Urology, Heilongjiang Provincial Hospital, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin, 150036, China.
Silong Xia *Department of Urology, Heilongjiang Provincial Hospital, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin, 150036, China.
Shiheng SunDepartment of Urology, Heilongjiang Provincial Hospital, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin, 150036, China. sshhljmnwk@163.com.

Funding

scientific research of the Heilongjiang Provincial Health Commission 20210404050337scientific research of the Heilongjiang Provincial Health Commission 20220404050660scientific research of the Heilongjiang Provincial Health Commission 20220404050752
6 · The paper itself

Abstract

Renal clear cell cancer (RCC) is a complex disease that is challenging to predict patient outcomes. Despite improvements with targeted therapy, personalized treatment planning is still needed. Artificial intelligence (AI) can help address this challenge by developing predictive models that accurately forecast patient survival periods. With AI-powered decision support, clinicians can provide patients with tailored treatment plans, enhancing treatment efficacy and quality of life. The study analyzed 267 patients with renal clear cell carcinoma, focusing on 26 who received targeted drug therapy. The data was refined by excluding 8 patients without enhanced CT scans. The research team categorized patients into two groups based on their expected lifespan: Group 1 (over 3 years) and Group 2 (under 3 years). The UPerNet algorithm was used to extract features from CT tumor markers, validating their effectiveness. These features were then used to develop an AI-based predictive model trained on the dataset. The developed AI model demonstrated remarkable accuracy, achieving a rate of 93.66% in Group 1 and 94.14% in Group 2. In conclusion, our study demonstrates the potential of AI technology in predicting the survival time of RCC patients undergoing targeted drug therapy. The established prediction model exhibits high predictive accuracy and stability, serving as a valuable tool for clinicians to facilitate the development of more personalized treatment plans for patients. This study highlights the importance of integrating AI technology in clinical decision-making, enabling patients to receive more effective and targeted treatment plans that enhance their overall quality of life.

Indexed as

Artificial IntelligenceCarcinoma, Renal CellKidney NeoplasmsAdultAgedAlgorithmsBiomarkers, TumorFemaleHumansMaleMiddle AgedMolecular Targeted TherapyPrecision MedicinePrognosisQuality of LifeTomography, X-Ray ComputedBiomarkers, TumorArtificial intelligenceCTImaging analysisRenal clear cell cancerTargeted therapy

Identifiers

PMID39478092
PMCPMC11525571

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.