Evidence map›Paper›PMID 39478091›Full record

ArticleScientific reports2024

Human prolyl hydroxylase domain 2 reacts with O

Giorgia Fiorini, Stephen A Marshall, William D Figg, William K Myers, Lennart Brewitz, Christopher J Schofield

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The research progress of α-ketoglutarate in osteoarthritis.Biochemistry and biophysics reports · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giorgia FioriniChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
Stephen A MarshallChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
William D FiggChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
William K MyersInorganic Chemistry Laboratory, Department of Chemistry, South Parks Road, Oxford, OX1 3QR, UK.
Lennart BrewitzChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
Christopher J SchofieldChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. christopher.schofield@chem.ox.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/J001694/2Biotechnology and Biological Sciences Research Council BB/L000121/1Biotechnology and Biological Sciences Research Council BB/R013829/1Cancer Research UK C8717/A18245EPSRC EP/L011972/1Wellcome TrustWellcome Trust 091857/7/10/7
6 · The paper itself

Abstract

Hypoxia inducible transcription factors (HIFs) mediate the hypoxic response in metazoans. When sufficient O

Indexed as

Hypoxia-Inducible Factor-Proline DioxygenasesKetoglutaric AcidsOxygenBasic Helix-Loop-Helix ProteinsCrystallography, X-RayEndothelial PAS Domain-Containing Protein 1HumansHydroxylationHypoxia-Inducible Factor 1, alpha SubunitModels, MolecularOxidation-ReductionProtein BindingBasic Helix-Loop-Helix ProteinsEGLN1 protein, humanEndothelial PAS Domain-Containing Protein 1Hypoxia-Inducible Factor 1, alpha SubunitHypoxia-Inducible Factor-Proline DioxygenasesKetoglutaric AcidsOxygenEpigeneticsHypoxia inducible factorHypoxia/oxygen sensingL-Ascorbic acid/vitamin CProlyl hydroxylase domain (PHD)/EGLN enzymeTranscriptional regulationα-Ketoglutarate/2-oxoglutarate oxygenase

Identifiers

PMID39478091
PMCPMC11525979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.