Evidence map›Paper›PMID 39478083›Full record

ReviewNature microbiology2024

A cross-systems primer for synthetic microbial communities.

Elijah C Mehlferber, Gontran Arnault, Bishnu Joshi, Laila P Partida-Martinez, Kathryn A Patras, Marie Simonin, Britt Koskella

Abstract readReview
In one paragraph

Review in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  17. Artificial soil (ArtSoil): Recreating soil conditions in synthetic plant growth media.The Plant journal : for cell and molecular biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elijah C MehlferberSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA. emehlferber@berkeley.edu.ORCID http://orcid.org/0000-0002-9958-3247
Gontran Arnault *Univ Angers, Institut Agro, INRAE, IRHS, SFR QUASAV, Angers, France.ORCID http://orcid.org/0000-0002-1694-6672
Bishnu Joshi *Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Laila P Partida-Martinez *Departamento de Ingeniería Genética, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav), Irapuato, México.
Kathryn A Patras *Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Marie SimoninUniv Angers, Institut Agro, INRAE, IRHS, SFR QUASAV, Angers, France.ORCID http://orcid.org/0000-0003-1493-881X
Britt KoskellaDepartment of Integrative Biology, University of California, Berkeley, CA, USA. bkoskella@berkeley.edu.ORCID http://orcid.org/0000-0003-1760-8496

Funding

Organoid Cultivation CoreU19AI157981 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MARESSO, ANTHONY W · 2021 to 2025
$12.4M
National Science Foundation (NSF) DBI-2209151NIAID NIH HHS U19 AI157981NSF | BIO | Division of Integrative Organismal Systems (IOS) 1838299
6 · The paper itself

Abstract

The design and use of synthetic communities, or SynComs, is one of the most promising strategies for disentangling the complex interactions within microbial communities, and between these communities and their hosts. Compared to natural communities, these simplified consortia provide the opportunity to study ecological interactions at tractable scales, as well as facilitating reproducibility and fostering interdisciplinary science. However, the effective implementation of the SynCom approach requires several important considerations regarding the development and application of these model systems. There are also emerging ethical considerations when both designing and deploying SynComs in clinical, agricultural or environmental settings. Here we outline current best practices in developing, implementing and evaluating SynComs across different systems, including a focus on important ethical considerations for SynCom research.

Indexed as

MicrobiotaHumansMicrobial ConsortiaMicrobial InteractionsSynthetic Biology

Identifiers

PMID39478083
PMCPMC11660114

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.