Evidence map›Paper›PMID 39477892›Full record

ReviewPharmacological reports : PR2025

Progress in the study of anti-tumor effects and mechanisms of vitexin.

Qiming Yang, Rui Huan, Defeng Meng, Junwei Qi, Lei Xia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmacological reports : PR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecules (Basel, Switzerland) · 2025
    Article
  4. Molecular Mechanisms of Vitexin: An Update on Its Anti-Cancer Functions.International journal of molecular sciences · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qiming YangSchool of Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0009-0001-7444-8954
Rui HuanSchool of Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0009-0009-2665-1438
Defeng MengSchool of Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0009-0004-1008-2553
Junwei QiSchool of Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0009-0005-8662-5777
Lei XiaSchool of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China. pathology001@sina.com.ORCID https://orcid.org/0000-0002-8073-6450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitexin (apigenin-8-C-beta-D-glucopyranoside) is a natural flavonoid derivative with anti-cancer, antioxidant, anti-inflammatory, antihypertensive, anti-asthma, anti-epilepsy, and other therapeutic effects. It is extracted from pearl millet, hawthorn, pigeon bean, mung bean, and other medicinal plants. Vitexin has received widespread attention because of its significant anti-tumor effect. It induces apoptosis and anti-tumor angiogenesis, inhibits tumor cell migration and invasion, regulates tumor cell autophagy and immunity, and increases patient sensitivity to radiotherapy and chemotherapy. It has a significant anti-tumor effect on breast, prostate, liver, cervical, and colon cancers, gliomas, and other malignant tumors. This review demonstrates the latest research progress on the anti-tumor effects and potential mechanisms of vitexin. It summarizes its anti-tumor mechanism to provide new theoretical support and reference for cancer treatment.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicApigeninNeoplasmsAnimalsApoptosisHumansNeovascularization, PathologicAntineoplastic AgentsAntineoplastic Agents, PhytogenicApigeninvitexinAnti-tumorMechanism of actionResearch progressSignal pathVitexin

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.