Evidence map›Paper›PMID 39477883›Full record

ArticleCurrent microbiology2024

Epidemiological and Genetic Insights of the Circulating Foot-and-Mouth Disease Virus Serotypes in Egypt.

Rabab T Hassanein, Hala K Abdelmegeed, Dina A Abdelwahed, Abeer G Zaki, Alaa S Saad, Momtaz A Shahein, Ahmed F Afify, Mohammed A Rohaim

Abstract read
In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rabab T HassaneinVirology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Hala K AbdelmegeedVirology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Dina A AbdelwahedVirology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Abeer G ZakiBiotechnology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Alaa S SaadBiotechnology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Momtaz A ShaheinVirology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Ahmed F AfifyVirology Research Department, Animal Health Research Institute, Agriculture Research Center (ARC), Dokki, Giza, 12618, Egypt.
Mohammed A RohaimDepartment of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt. m.a.rohaim@lancaster.ac.uk.ORCID http://orcid.org/0000-0003-1798-7086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foot-and-mouth disease virus (FMDV) remains a major threat to livestock in Egypt, with ongoing outbreaks involving serotypes A, O, and SAT2. This study aimed to improve the understanding of these circulating FMDV strains to improve control measures. Between 2022 and 2023, 134 cattle samples from across Egypt were analyzed, revealing a 67.9% positivity rate for Pan FMDV. Of these positive samples, 64 were identified as serotype A and 27 as serotype O. Genetic analysis indicated that serotype O strains clustered within the EA-3 topotype, suggesting endemic persistence and potential vaccine evasion, while serotype A strains were associated with the African topotype and linked to regions such as Ethiopia, Kenya, and Sudan. Notable amino acid mutations in the VP1 protein of both serotypes highlighted potential challenges to vaccine effectiveness. These findings underscore the need for enhanced surveillance, timely vaccine updates, and regional cooperation to effectively manage FMD outbreaks in Egypt and neighboring countries.

Indexed as

Cattle DiseasesFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusPhylogenySerogroupAnimalsCapsid ProteinsCattleDisease OutbreaksEgyptCapsid Proteins

Identifiers

PMID39477883
PMCPMC11525254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.