Evidence map›Paper›PMID 39477543›Full record

ArticleLife science alliance2025

PTPN1/2 inhibition promotes muscle stem cell differentiation in Duchenne muscular dystrophy.

Yiyang Liu, Shulei Li, Rebecca Robertson, Jules A Granet, Isabelle Aubry, Romina L Filippelli, Michel L Tremblay, Natasha C Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mouse Trophoblast Stem Cells Are Deficient in TNFα-Activated NFκB Signaling Pathway and Inflammatory Response.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Article
  2. Article
  3. Article
  4. Stem/progenitor cell-based therapy for Duchenne muscular dystrophy.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiyang LiuDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.
Shulei LiDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.
Rebecca RobertsonDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.ORCID 0000-0001-6159-6942
Jules A GranetDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.ORCID 0009-0000-0603-7400
Isabelle AubryDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.
Romina L FilippelliDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.ORCID 0000-0003-1824-3767
Michel L TremblayDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada.ORCID 0000-0002-0281-541X
Natasha C ChangDepartment of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montréal, Canada natasha.chang@mcgill.ca.ORCID 0000-0003-0589-9660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a lethal disease caused by mutations in the

Indexed as

Cell DifferentiationMice, Inbred mdxMuscular Dystrophy, DuchenneProtein Tyrosine Phosphatase, Non-Receptor Type 1Protein Tyrosine Phosphatase, Non-Receptor Type 2STAT3 Transcription FactorAnimalsDisease Models, AnimalHumansMiceMuscle DevelopmentMuscle, SkeletalPhosphorylationSignal TransductionStem CellsProtein Tyrosine Phosphatase, Non-Receptor Type 1Protein Tyrosine Phosphatase, Non-Receptor Type 2PTPN1 protein, humanPTPN2 protein, humanSTAT3 Transcription Factor

Identifiers

PMID39477543
PMCPMC11527974

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.